Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2181463..2181726 Replicon chromosome
Accession NZ_CP128387
Organism Staphylococcus aureus strain 22-042

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag QTN90_RS10455 Protein ID WP_001802298.1
Coordinates 2181463..2181567 (+) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF2
Locus tag -
Coordinates 2181562..2181726 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QTN90_RS10420 (QTN90_10420) 2177362..2177913 + 552 WP_289211166.1 TIR domain-containing protein -
QTN90_RS10425 (QTN90_10425) 2178260..2179042 + 783 WP_000908191.1 ABC transporter ATP-binding protein -
QTN90_RS10430 (QTN90_10430) 2179110..2179967 + 858 WP_000370942.1 HAD family hydrolase -
QTN90_RS10435 (QTN90_10435) 2180097..2180189 - 93 WP_000220902.1 hypothetical protein -
QTN90_RS10440 (QTN90_10440) 2180625..2180783 - 159 WP_001792784.1 hypothetical protein -
QTN90_RS10445 (QTN90_10445) 2180776..2180946 - 171 WP_001807897.1 hypothetical protein -
QTN90_RS10450 (QTN90_10450) 2181204..2181302 + 99 Protein_2052 resolvase -
QTN90_RS10455 (QTN90_10455) 2181463..2181567 + 105 WP_001802298.1 hypothetical protein Toxin
- 2181562..2181726 - 165 - - Antitoxin
QTN90_RS10465 (QTN90_10465) 2182131..2183222 - 1092 WP_000495673.1 hypothetical protein -
QTN90_RS10470 (QTN90_10470) 2183488..2184468 - 981 WP_000019735.1 CDF family zinc efflux transporter CzrB -
QTN90_RS10475 (QTN90_10475) 2184470..2184790 - 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
QTN90_RS10480 (QTN90_10480) 2184942..2185607 + 666 WP_001024099.1 SDR family oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T284516 WP_001802298.1 NZ_CP128387:2181463-2181567 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

Antitoxin


Download         Length: 165 bp

>AT284516 NZ_CP128387:c2181726-2181562 [Staphylococcus aureus]
GTAGTAAGTAGAAGCAAAAGATGAAAATCTTTAACTCTTGAAACACAAAAAGGGCAACACTCGGAAACATGTTACCCTAA
TGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAAATGCCGGTCAAAGCGAATAGAAGGT
TATTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References