Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) DinJ-YafQ (relBE)/YafQ-RelB
Location 364243..364781 Replicon chromosome
Accession NZ_CP128261
Organism Salmonella enterica subsp. enterica serovar Heidelberg isolate FT3-7B

Toxin (Protein)


Gene name yafQ Uniprot ID A0A8E7RBX8
Locus tag QR684_RS01660 Protein ID WP_001682450.1
Coordinates 364506..364781 (+) Length 92 a.a.

Antitoxin (Protein)


Gene name dinJ Uniprot ID A0A7U1KUN1
Locus tag QR684_RS01655 Protein ID WP_000729714.1
Coordinates 364243..364503 (+) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QR684_RS01640 (359954) 359954..361507 + 1554 WP_000013007.1 TROVE domain-containing protein -
QR684_RS01645 (361855) 361855..363069 + 1215 WP_001105530.1 RNA-splicing ligase RtcB -
QR684_RS01650 (363073) 363073..364134 + 1062 WP_000101032.1 RNA 3'-terminal phosphate cyclase -
QR684_RS01655 (364243) 364243..364503 + 261 WP_000729714.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
QR684_RS01660 (364506) 364506..364781 + 276 WP_001682450.1 type II toxin-antitoxin system YafQ family toxin Toxin
QR684_RS01665 (364869) 364869..367574 - 2706 WP_001531645.1 HTH-type transcriptional regulator MalT -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(4-91)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(4-84)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10605.16 Da        Isoelectric Point: 8.9063

>T284493 WP_001682450.1 NZ_CP128261:364506-364781 [Salmonella enterica subsp. enterica serovar Heidelberg]
MGQREIEYSGQFQKDVKRAQKRHKDVGKLKTLMTLLIHHPFPLPAIYKDHPLQGSYSGYRDAHIGPDWILVDKITDECLR
FERTGTHADLF

Download         Length: 276 bp

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9445.82 Da        Isoelectric Point: 4.6028

>AT284493 WP_000729714.1 NZ_CP128261:364243-364503 [Salmonella enterica subsp. enterica serovar Heidelberg]
MAANALVRARIDETLKNQAADVLAEMGLTISDLIRITLTKVAREKALPFDLRIPNELTSRTIENSEAGVDIHKAKDADDL
FDQLGI

Download         Length: 261 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A7U1KUN1

References