Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/HigB-HigA
Location 6328262..6328853 Replicon chromosome
Accession NZ_CP128260
Organism Pseudomonas fluorescens strain PH.SM

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag QR290_RS28615 Protein ID WP_115079644.1
Coordinates 6328575..6328853 (-) Length 93 a.a.

Antitoxin (Protein)


Gene name graA Uniprot ID -
Locus tag QR290_RS28610 Protein ID WP_115079643.1
Coordinates 6328262..6328567 (-) Length 102 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QR290_RS28580 (QR290_28580) 6323683..6324387 + 705 WP_289204052.1 HAD-IA family hydrolase -
QR290_RS28585 (QR290_28585) 6324453..6324779 - 327 WP_007951900.1 transcriptional regulator SutA -
QR290_RS28590 (QR290_28590) 6324882..6325307 - 426 WP_039765261.1 secondary thiamine-phosphate synthase enzyme YjbQ -
QR290_RS28595 (QR290_28595) 6325523..6326860 - 1338 WP_007951904.1 ammonium transporter -
QR290_RS28600 (QR290_28600) 6326898..6327236 - 339 WP_002555808.1 P-II family nitrogen regulator -
QR290_RS28605 (QR290_28605) 6327635..6327895 + 261 WP_007920416.1 accessory factor UbiK family protein -
QR290_RS28610 (QR290_28610) 6328262..6328567 - 306 WP_115079643.1 HigA family addiction module antitoxin Antitoxin
QR290_RS28615 (QR290_28615) 6328575..6328853 - 279 WP_115079644.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
QR290_RS28620 (QR290_28620) 6329179..6330672 + 1494 WP_085606079.1 YifB family Mg chelatase-like AAA ATPase -
QR290_RS28625 (QR290_28625) 6330778..6332754 - 1977 WP_115079667.1 methyl-accepting chemotaxis protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-1

(1-92)

Antitoxin

Cro/C1-type helix-turn-helix domain

(18-69)


Sequences

Toxin        


Download         Length: 93 a.a.        Molecular weight: 10566.09 Da        Isoelectric Point: 6.9493

>T284491 WP_115079644.1 NZ_CP128260:c6328853-6328575 [Pseudomonas fluorescens]
MIVSFRCSETEYLFRSGKTRFWSAILSVAERKLTMLDAAAVLADLRSPPGNRLETLEGDRKGQYSIRINAQWRICFVWGL
NGPEDVEIVDYH

Download         Length: 279 bp

Antitoxin


Download         Length: 102 a.a.        Molecular weight: 11248.97 Da        Isoelectric Point: 6.4556

>AT284491 WP_115079643.1 NZ_CP128260:c6328567-6328262 [Pseudomonas fluorescens]
MTKNGMRPVHPGEILKEEYLEPLSLTAAALARALSVSTPTVNDIVLQRRGISADMALRLSICLDTTPEFWLNLQSTYDLR
KAEIERGASIRDQVERLAHCA

Download         Length: 306 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References