Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/-
Location 4247089..4247744 Replicon chromosome
Accession NZ_CP128260
Organism Pseudomonas fluorescens strain PH.SM

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag QR290_RS18960 Protein ID WP_096822369.1
Coordinates 4247089..4247433 (+) Length 115 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag QR290_RS18965 Protein ID WP_115078473.1
Coordinates 4247430..4247744 (+) Length 105 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QR290_RS18945 (QR290_18945) 4243184..4244716 + 1533 WP_007951464.1 NADH-quinone oxidoreductase subunit M -
QR290_RS18950 (QR290_18950) 4244724..4246187 + 1464 WP_011334964.1 NADH-quinone oxidoreductase subunit NuoN -
QR290_RS18955 (QR290_18955) 4246246..4246719 - 474 WP_115078472.1 GNAT family N-acetyltransferase -
QR290_RS18960 (QR290_18960) 4247089..4247433 + 345 WP_096822369.1 toxin Toxin
QR290_RS18965 (QR290_18965) 4247430..4247744 + 315 WP_115078473.1 transcriptional regulator Antitoxin
QR290_RS18970 (QR290_18970) 4247905..4249230 + 1326 WP_115078474.1 OprD family porin -
QR290_RS18975 (QR290_18975) 4249380..4249712 - 333 WP_115078475.1 DUF2790 domain-containing protein -
QR290_RS18980 (QR290_18980) 4249792..4249992 - 201 WP_115078476.1 co-regulatory protein PtrA N-terminal domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(41-100)


Sequences

Toxin        


Download         Length: 115 a.a.        Molecular weight: 13569.38 Da        Isoelectric Point: 6.9816

>T284489 WP_096822369.1 NZ_CP128260:4247089-4247433 [Pseudomonas fluorescens]
MDALFIELPAFQKHRDDYLDDDLFRSFQLELLKNPEAGDLIEGTGGLRKIRFCDQRRGKGKRSGLRVIYYWWSGFDQFWL
FTVYSKNEQDDLLPSQKRVFKQALDTEINTRTQI

Download         Length: 345 bp

Antitoxin


Download         Length: 105 a.a.        Molecular weight: 11943.81 Da        Isoelectric Point: 9.9898

>AT284489 WP_115078473.1 NZ_CP128260:4247430-4247744 [Pseudomonas fluorescens]
MKRDIFSELMEGLEALADERQSKVTLRTHKVQLPKLLPITAEEVVAIRQQLNLSRSVFAMYLRTNTRTLENWEQGRATPN
AQATTLIRLVERFPQTIDHLAALT

Download         Length: 315 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References