284484

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/RelE-HTH
Location 545741..546345 Replicon chromosome
Accession NZ_CP128260
Organism Pseudomonas fluorescens strain PH.SM

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag QR290_RS02405 Protein ID WP_115076186.1
Coordinates 546031..546345 (-) Length 105 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag QR290_RS02400 Protein ID WP_115076185.1
Coordinates 545741..546028 (-) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QR290_RS02385 (QR290_02385) 541802..543343 + 1542 WP_289204252.1 phosphoenolpyruvate carboxykinase -
QR290_RS02390 (QR290_02390) 543390..544031 - 642 WP_162803799.1 hypothetical protein -
QR290_RS02395 (QR290_02395) 544028..544900 - 873 WP_162803800.1 hypothetical protein -
QR290_RS02400 (QR290_02400) 545741..546028 - 288 WP_115076185.1 NadS family protein Antitoxin
QR290_RS02405 (QR290_02405) 546031..546345 - 315 WP_115076186.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
QR290_RS02410 (QR290_02410) 546457..546756 - 300 WP_115076187.1 hypothetical protein -
QR290_RS02415 (QR290_02415) 547307..548434 - 1128 WP_289204253.1 hypothetical protein -
QR290_RS02420 (QR290_02420) 548539..548820 - 282 WP_205350838.1 hypothetical protein -
QR290_RS02425 (QR290_02425) 549125..549628 + 504 WP_289204254.1 polysaccharide deacetylase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-2

(42-100)

Antitoxin

Cro/C1-type helix-turn-helix domain

(35-86)


Sequences

Toxin        


Download         Length: 105 a.a.        Molecular weight: 11833.73 Da        Isoelectric Point: 10.3534

>T284484 WP_115076186.1 NZ_CP128260:c546345-546031 [Pseudomonas fluorescens]
MIFVETRIFTRRVKELLDDDTYAAFQKQLVVSPSIGDVIEGTGGIRKTRIAAKGHGKRGGARVIYYHFVSASQIGLLMIY
PKNEQHDLSSDERKALKVLIEKWR

Download         Length: 315 bp

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10713.31 Da        Isoelectric Point: 6.7193

>AT284484 WP_115076185.1 NZ_CP128260:c546028-545741 [Pseudomonas fluorescens]
MSKFFDELMESVQEMDEIVRGERTPSREFHVDALQVKEIRKATGLTQAKFAALIDVQLGTLRNWEQGRREPTGPAKALLK
AIHNDPVHVLNALAC

Download         Length: 288 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References