Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) prlF-yhaV (relBE)/YhaV-PrlF
Location 2763519..2764312 Replicon chromosome
Accession NZ_CP128233
Organism Paralcaligenes sp. CC-YST667

Toxin (Protein)


Gene name yhaV Uniprot ID -
Locus tag N7E01_RS15270 Protein ID WP_289173497.1
Coordinates 2763845..2764312 (+) Length 156 a.a.

Antitoxin (Protein)


Gene name prlF Uniprot ID -
Locus tag N7E01_RS15265 Protein ID WP_289173496.1
Coordinates 2763519..2763848 (+) Length 110 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N7E01_RS15240 (N7E01_15240) 2758822..2759208 - 387 WP_289173492.1 hypothetical protein -
N7E01_RS15245 (N7E01_15245) 2759151..2760617 - 1467 WP_289173493.1 metallophosphoesterase -
N7E01_RS15250 (N7E01_15250) 2761114..2762327 + 1214 Protein_2999 sulfatase-like hydrolase/transferase -
N7E01_RS15255 (N7E01_15255) 2762389..2763060 + 672 WP_289173494.1 hypothetical protein -
N7E01_RS15260 (N7E01_15260) 2763029..2763283 + 255 WP_289173495.1 dockerin type I domain-containing protein -
N7E01_RS15265 (N7E01_15265) 2763519..2763848 + 330 WP_289173496.1 type II toxin-antitoxin system PrlF family antitoxin Antitoxin
N7E01_RS15270 (N7E01_15270) 2763845..2764312 + 468 WP_289173497.1 type II toxin-antitoxin system YhaV family toxin Toxin
N7E01_RS15275 (N7E01_15275) 2764428..2764862 + 435 WP_289173498.1 transposase -
N7E01_RS15280 (N7E01_15280) 2764903..2765190 + 288 WP_289173404.1 IS66 family insertion sequence element accessory protein TnpB -
N7E01_RS15285 (N7E01_15285) 2765339..2765500 + 162 Protein_3006 transposase -
N7E01_RS15290 (N7E01_15290) 2765599..2766273 + 675 WP_289173405.1 IS66 family transposase -
N7E01_RS15295 (N7E01_15295) 2766254..2766585 + 332 Protein_3008 transposase -
N7E01_RS15300 (N7E01_15300) 2766661..2766837 + 177 WP_289175826.1 transposase domain-containing protein -
N7E01_RS15305 (N7E01_15305) 2767329..2767571 - 243 WP_289173499.1 ATP-binding protein -
N7E01_RS15310 (N7E01_15310) 2767674..2769038 + 1365 Protein_3011 IS5 family transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - - 2672837..2769058 96221


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin endonuclease, YhaV

(16-152)

Antitoxin

PrlF antitoxin

(8-107)


Sequences

Toxin        


Download         Length: 156 a.a.        Molecular weight: 17990.52 Da        Isoelectric Point: 9.7079

>T284457 WP_289173497.1 NZ_CP128233:2763845-2764312 [Paralcaligenes sp. CC-YST667]
MSARKPEPLVIHGWTVFAHPLFLAQIEALVRQVESLKQKDPAGYVKKNASKRLAAITKLAFDVIPQDPTRPEYRQGGALG
DDHKHWFRAKFFQQYRLFFRYHAPSKVIVYAWVSDEDTKRAYESSDDAYRVFRKMLESGHPPDDWDQLLAEAVTK

Download         Length: 468 bp

Antitoxin


Download         Length: 110 a.a.        Molecular weight: 11781.23 Da        Isoelectric Point: 4.5267

>AT284457 WP_289173496.1 NZ_CP128233:2763519-2763848 [Paralcaligenes sp. CC-YST667]
MAATLEVESTLTDRYQTTVPETVRRALKLGKRDKIHYTIHPSGDVVLTRVEASDGDDPVLGQFLAFLAADITRHPERLQA
VDAGLAQRLQALVGGVDVDLNAALSADDE

Download         Length: 330 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References