284407

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/Txe-YefM
Location 513832..514352 Replicon chromosome
Accession NZ_CP128214
Organism Agrobacterium fabrum strain ARqua1

Toxin (Protein)


Gene name yoeB Uniprot ID A9CID9
Locus tag QOV31_RS02450 Protein ID WP_010972002.1
Coordinates 514083..514352 (+) Length 90 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID Q7CY23
Locus tag QOV31_RS02445 Protein ID WP_010972003.1
Coordinates 513832..514086 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QOV31_RS02425 (QOV31_000486) 509432..510478 - 1047 WP_006311839.1 NAD(P)-dependent alcohol dehydrogenase -
QOV31_RS02430 (QOV31_000487) 510668..511573 + 906 WP_010972005.1 AraC family transcriptional regulator -
QOV31_RS02435 (QOV31_000488) 511973..512626 + 654 WP_006311841.1 TetR/AcrR family transcriptional regulator -
QOV31_RS02440 (QOV31_000489) 512674..513693 + 1020 WP_010972004.1 ketol-acid reductoisomerase -
QOV31_RS02445 (QOV31_000490) 513832..514086 + 255 WP_010972003.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
QOV31_RS02450 (QOV31_000491) 514083..514352 + 270 WP_010972002.1 Txe/YoeB family addiction module toxin Toxin
QOV31_RS02455 (QOV31_000492) 514357..514806 - 450 WP_010972001.1 RbsD/FucU family protein -
QOV31_RS02460 (QOV31_000493) 515081..516325 + 1245 WP_010972000.1 PLP-dependent aminotransferase family protein -
QOV31_RS02465 (QOV31_000494) 516634..517617 + 984 WP_010971999.1 ABC transporter substrate-binding protein -
QOV31_RS02470 (QOV31_000495) 517627..519321 + 1695 WP_010971998.1 iron ABC transporter permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-88)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 90 a.a.        Molecular weight: 10612.09 Da        Isoelectric Point: 9.8742

>T284407 WP_010972002.1 NZ_CP128214:514083-514352 [Agrobacterium fabrum]
MKLVWTLSSWDDYEFWQRTDARMVEKINDLIRNAKRTPFAGLGKPEPLKGDMAGYWSRRITAEHRFVYRVSGSGSEQRLE
VIQCRFHYQ

Download         Length: 270 bp

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9577.70 Da        Isoelectric Point: 4.6749

>AT284407 WP_010972003.1 NZ_CP128214:513832-514086 [Agrobacterium fabrum]
MANVRFTEFRQNFATHFDRVLETRAPLLVTRQGKEAVVVLAEGEYESMQETLHLLSNPANASRLRASMGELERGDTIERD
PTEE

Download         Length: 255 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
PDB 6N90

Antitoxin

Source ID Structure
AlphaFold DB Q7CY23

References