284404

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) HipBST/HipA(toxin)
Location 448304..449660 Replicon chromosome
Accession NZ_CP128204
Organism Vibrio furnissii strain VFBJ05

Toxin (Protein)


Gene name HipT Uniprot ID -
Locus tag QSU95_RS02160 Protein ID WP_286211622.1
Coordinates 448304..449350 (-) Length 349 a.a.

Antitoxin (Protein)


Gene name HipS Uniprot ID -
Locus tag QSU95_RS02165 Protein ID WP_286211623.1
Coordinates 449334..449660 (-) Length 109 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QSU95_RS02130 (QSU95_02130) 443557..443901 - 345 WP_286211616.1 TraK family protein -
QSU95_RS02135 (QSU95_02135) 443903..444142 - 240 WP_222732883.1 helix-turn-helix domain-containing protein -
QSU95_RS02140 (QSU95_02140) 444737..445528 + 792 WP_286211618.1 sce7726 family protein -
QSU95_RS02145 (QSU95_02145) 445556..446704 - 1149 WP_286211619.1 beta family protein -
QSU95_RS02150 (QSU95_02150) 446718..447218 - 501 WP_286211620.1 ImmA/IrrE family metallo-endopeptidase -
QSU95_RS02155 (QSU95_02155) 447215..447859 - 645 WP_286211621.1 hypothetical protein -
QSU95_RS02160 (QSU95_02160) 448304..449350 - 1047 WP_286211622.1 HipA domain-containing protein Toxin
QSU95_RS02165 (QSU95_02165) 449334..449660 - 327 WP_286211623.1 HipA N-terminal domain-containing protein Antitoxin
QSU95_RS02170 (QSU95_02170) 449645..449965 - 321 WP_055467269.1 helix-turn-helix transcriptional regulator -
QSU95_RS02175 (QSU95_02175) 450270..450695 + 426 WP_113606155.1 bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD -
QSU95_RS02180 (QSU95_02180) 451018..451674 + 657 WP_286211628.1 hypothetical protein -
QSU95_RS02185 (QSU95_02185) 451797..452627 + 831 WP_286211630.1 abortive infection family protein -
QSU95_RS02190 (QSU95_02190) 452880..453971 - 1092 WP_060658328.1 site-specific integrase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 431009..451674 20665


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HipA-like, C-terminal

(60-309)

Antitoxin

HipA, N-terminal subdomain 1

(6-98)


Sequences

Toxin        


Download         Length: 349 a.a.        Molecular weight: 39409.84 Da        Isoelectric Point: 4.8631

>T284404 WP_286211622.1 NZ_CP128204:c449350-448304 [Vibrio furnissii]
MYPSNRSLISLDDLNEQNREQVEYKKGEIKTLLGSNKFQIQLPFSRAEFVTELPKKQKGMSISGYQPKLSLAINDDNQLG
VVEDKALFILKPSPEEFPHLAENEHATMLVMKFLGFDTPPFGLVRFNEPDGEGELAFMIRRYDRLNAGEEAIHQEQLDAA
MAVPEKYGKTQGDAEGYVSYEQACKFLIHQVDGSLNFKKELFNRILVAYFLGNNDLHLRNIGLLLPEQEATRLAPIYDYV
SIAPYPGYIANENPLALPLLASEEGDNFNTSGYQSHSTYTGYDFLTFAQNIGLSPKLATKMIKDLCAKQEAILNIYRNSF
MLPEHVEKVAEWILSRINYLGQLEHVAV

Download         Length: 1047 bp

Antitoxin


Download         Length: 109 a.a.        Molecular weight: 12317.18 Da        Isoelectric Point: 5.7364

>AT284404 WP_286211623.1 NZ_CP128204:c449660-449334 [Vibrio furnissii]
MDRKVKVLLYGKFCGVLTQNEQGFLFEYEPGYRGRSLSLSMPVADGPFESKELHPFFLSLAPEGWLKKRYSELQKIDEND
PLGMLLSNGKNLLGAVQLLRLEEHVSEQ

Download         Length: 327 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References