Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/Txe-RelB
Location 1610405..1610919 Replicon chromosome
Accession NZ_CP128169
Organism Limosilactobacillus fermentum strain RC4

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag QSU93_RS08255 Protein ID WP_286102252.1
Coordinates 1610405..1610668 (-) Length 88 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag QSU93_RS08260 Protein ID WP_100352120.1
Coordinates 1610665..1610919 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QSU93_RS08235 (QSU93_08235) 1605744..1606610 - 867 WP_286102249.1 Gfo/Idh/MocA family oxidoreductase -
QSU93_RS08240 (QSU93_08240) 1606568..1606783 - 216 WP_286102250.1 hypothetical protein -
QSU93_RS08245 (QSU93_08245) 1607447..1608361 + 915 WP_286102251.1 hypothetical protein -
QSU93_RS08250 (QSU93_08250) 1608874..1609995 + 1122 WP_205303642.1 PTS sugar transporter subunit IIC -
QSU93_RS08255 (QSU93_08255) 1610405..1610668 - 264 WP_286102252.1 Txe/YoeB family addiction module toxin Toxin
QSU93_RS08260 (QSU93_08260) 1610665..1610919 - 255 WP_100352120.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
QSU93_RS08265 (QSU93_08265) 1611104..1611732 - 629 Protein_1582 family 1 glycosylhydrolase -
QSU93_RS08270 (QSU93_08270) 1611983..1612642 - 660 WP_286102253.1 3,4-dihydroxy-2-butanone-4-phosphate synthase -
QSU93_RS08275 (QSU93_08275) 1613036..1614322 - 1287 WP_286102254.1 ISL3 family transposase -
QSU93_RS08280 (QSU93_08280) 1614413..1615399 - 987 WP_286102255.1 IS30 family transposase -
QSU93_RS08285 (QSU93_08285) 1615633..1615782 + 150 Protein_1586 IS5/IS1182 family transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(4-86)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(3-55)


Sequences

Toxin        


Download         Length: 88 a.a.        Molecular weight: 10315.01 Da        Isoelectric Point: 10.3042

>T284367 WP_286102252.1 NZ_CP128169:c1610668-1610405 [Limosilactobacillus fermentum]
MSYAIKLKRSANKDLKKIKGSYLEKSFLQIIEQLRKDTLAPNQGFEKLVPPIKGFYSRRINIQYRLVYKVDQDTQTVIIY
SAWSHYE

Download         Length: 264 bp

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9775.07 Da        Isoelectric Point: 4.4237

>AT284367 WP_100352120.1 NZ_CP128169:c1610919-1610665 [Limosilactobacillus fermentum]
MDQIVTPTQARKDLFKIIKRINENNEPVVIKPTKADEKSVVVISEDDWKAIQETLFLVNHGVDKQIKERENEPLDDFDDV
WGQL

Download         Length: 255 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References