Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-YefM
Location 1891728..1892242 Replicon chromosome
Accession NZ_CP127409
Organism Rhodanobacter thiooxydans strain C33

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag QQA13_RS08540 Protein ID WP_108472894.1
Coordinates 1891728..1891982 (-) Length 85 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag QQA13_RS08545 Protein ID WP_108472895.1
Coordinates 1891994..1892242 (-) Length 83 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QQA13_RS08525 1886800..1889202 - 2403 WP_108472892.1 phosphoketolase family protein -
QQA13_RS08530 1889371..1890657 + 1287 WP_108472893.1 divalent metal cation transporter -
QQA13_RS08535 1890773..1891447 - 675 WP_286042670.1 aspartate/glutamate racemase family protein -
QQA13_RS08540 1891728..1891982 - 255 WP_108472894.1 Txe/YoeB family addiction module toxin Toxin
QQA13_RS08545 1891994..1892242 - 249 WP_108472895.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
QQA13_RS08550 1892722..1893969 + 1248 WP_108472905.1 integrase arm-type DNA-binding domain-containing protein -
QQA13_RS08555 1894048..1894413 + 366 WP_159082223.1 hypothetical protein -
QQA13_RS08560 1894410..1894640 + 231 WP_108472906.1 hypothetical protein -
QQA13_RS08565 1894706..1895383 + 678 WP_159082224.1 hypothetical protein -
QQA13_RS08570 1895501..1895710 + 210 WP_108472908.1 AlpA family transcriptional regulator -
QQA13_RS08575 1895707..1895907 + 201 WP_108472909.1 hypothetical protein -
QQA13_RS08580 1895904..1896434 + 531 WP_199909881.1 hypothetical protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(5-84)

Antitoxin

(1-73)


Sequences


Toxin        


Download         Length: 85 a.a.        Molecular weight: 10021.47 Da        Isoelectric Point: 8.5114

>T284251 WP_108472894.1 NZ_CP127409:c1891982-1891728 [Rhodanobacter thiooxydans]
MQLIFSDSAWEDYLHWQAHDRKLVARINKLIDDTLRHPLEGIGKPEPLRHGLAGYWSRRINDEHRMVYKPTADALLIAQL
RYHY

Download         Length: 255 bp


Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9264.67 Da        Isoelectric Point: 8.0002

>AT284251 WP_108472895.1 NZ_CP127409:c1892242-1891994 [Rhodanobacter thiooxydans]
MDTITYTKARSSLAETMERVCEDHAPVIITKKDESVVMMSLADYQSMEETAYLLRSPRNARRLLESMAQLESGGGKPRKL
AR

Download         Length: 249 bp


Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References