Detailed information of TA system TA284234

Bioinformatically predicted

Overview

TA module

• Type: VII
• Classification (family/domain): TglT-TakA/AbiEii(toxin)
• Location: 1302780..1304149
• Replicon: chromosome
• Accession: NZ_CP127390
• Organism: Propionimicrobium sp. PCR01-08-3

Toxin (Protein)

• Gene name: tglT
• Uniprot ID: -
• Locus tag: QQ658_RS05965
• Protein ID: WP_286026739.1
• Coordinates: 1303319..1304149 (+)
• Length: 277 a.a.

Antitoxin (Protein)

• Gene name: takA
• Uniprot ID: -
• Locus tag: QQ658_RS05960
• Protein ID: WP_286026738.1
• Coordinates: 1302780..1303322 (+)
• Length: 181 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
QQ658_RS05945 (QQ658_05945)	1298416..1299753	+	1338	WP_286026735.1	histidine--tRNA ligase	-
QQ658_RS05950 (QQ658_05950)	1299925..1301757	+	1833	WP_286026736.1	aspartate--tRNA ligase	-
QQ658_RS05955 (QQ658_05955)	1301918..1302697	+	780	WP_286026737.1	tyrosine-protein phosphatase	-
QQ658_RS05960 (QQ658_05960)	1302780..1303322	+	543	WP_286026738.1	hypothetical protein	Antitoxin
QQ658_RS05965 (QQ658_05965)	1303319..1304149	+	831	WP_286026739.1	nucleotidyl transferase AbiEii/AbiGii toxin family protein	Toxin
QQ658_RS05970 (QQ658_05970)	1304409..1305725	+	1317	WP_286027046.1	replication-associated recombination protein A	-
QQ658_RS05975 (QQ658_05975)	1305957..1306964	-	1008	WP_286026740.1	YihY/virulence factor BrkB family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Nucleotidyl transferase AbiEii toxin, Type IV TA system (48-231)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 277 a.a.
• Molecular weight: 30609.73 Da
• Isoelectric Point: 5.0786

>T284234 WP_286026739.1 NZ_CP127390:1303319-1304149 [Propionimicrobium sp. PCR01-08-3]
MSYSSAPTSVRSLEQRIRNVEGDEGLALRRRITMALVVVGQMLPEGAIKGGSAMALRYGRRTRFTRDLDAARVTPLRTFR
NEFEESLSAGWAGFTGRLVEKAAPRPPAVPTAYVMQPFAVKLDYWGRAWCTVSFELGHNEIGDADEPEYRLSTELVDLFT
EVGLEAPKPVPVMRVDHQVAQKLHAVSAEGSERARDLVDLQLLHDGEDLDLARVAATCVRLFDYRQQQAWPPVIAGSNNW
TTLYAEAAEGLNVIPAVEEAVDWVNEFVRRIAASIG

Nucleotide

• Length: 831 bp

Antitoxin

Protein

• Length: 181 a.a.
• Molecular weight: 19769.47 Da
• Isoelectric Point: 7.3557

>AT284234 WP_286026738.1 NZ_CP127390:1302780-1303322 [Propionimicrobium sp. PCR01-08-3]
MAADVKYRDAVREVARDHYGYVTTSQAAEAGVPAVELPKLTARGGLEHVAYGLYRVSDIPRAPYDQFAEALLRAGEGAYL
HGESVLALFGLADVNPRRIKVAVRRRTRPTLPPFMELTQVKGEAHTTLYEGLAAQPVADAILECRGRIETERLLEAAKQA
RSEGLLTTSEWRQVQNGLPS

Nucleotide

• Length: 543 bp