Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) prlF-yhaV (relBE)/YhaV-PrlF
Location 3481184..3482021 Replicon chromosome
Accession NZ_CP127389
Organism Proteus sp. HZ0627

Toxin (Protein)


Gene name yhaV Uniprot ID -
Locus tag QQS39_RS16000 Protein ID WP_285804914.1
Coordinates 3481527..3482021 (+) Length 165 a.a.

Antitoxin (Protein)


Gene name prlF Uniprot ID -
Locus tag QQS39_RS15995 Protein ID WP_151436112.1
Coordinates 3481184..3481516 (+) Length 111 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QQS39_RS15985 (QQS39_15985) 3477736..3479175 - 1440 WP_285804912.1 alkaline phosphatase -
QQS39_RS15990 (QQS39_15990) 3479406..3480962 - 1557 WP_285804913.1 alpha/beta hydrolase-fold protein -
QQS39_RS15995 (QQS39_15995) 3481184..3481516 + 333 WP_151436112.1 type II toxin-antitoxin system PrlF family antitoxin Antitoxin
QQS39_RS16000 (QQS39_16000) 3481527..3482021 + 495 WP_285804914.1 type II toxin-antitoxin system YhaV family toxin Toxin
QQS39_RS16005 (QQS39_16005) 3482120..3483259 - 1140 WP_151436114.1 ElyC/SanA/YdcF family protein -
QQS39_RS16010 (QQS39_16010) 3483643..3484887 - 1245 WP_285804915.1 multifunctional transcriptional regulator/nicotinamide-nucleotide adenylyltransferase/ribosylnicotinamide kinase NadR -
QQS39_RS16015 (QQS39_16015) 3484899..3486290 - 1392 WP_165122335.1 DNA repair protein RadA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin endonuclease, YhaV

(11-147)

Antitoxin

PrlF antitoxin

(13-110)


Sequences

Toxin        


Download         Length: 165 a.a.        Molecular weight: 18877.78 Da        Isoelectric Point: 10.0167

>T284226 WP_285804914.1 NZ_CP127389:3481527-3482021 [Proteus sp. HZ0627]
MDTLEINGWKIFFHQCFLDQIIELIENVKKLKASDPSGYKKKSATKLLTAIKKVIEERIARNPLDPIFHLGNTLGSNNKH
WFRAKFLQQFRLFFRCSEEHKIIVIGLVNDFNTLRAYDSKSDAYKVFSSKLKAGKPPNDWQTLLKEASATAGAETLSIQD
FFNH

Download         Length: 495 bp

Antitoxin


Download         Length: 111 a.a.        Molecular weight: 12399.15 Da        Isoelectric Point: 4.3332

>AT284226 WP_151436112.1 NZ_CP127389:3481184-3481516 [Proteus sp. HZ0627]
MILNIEDVSLRAESRLTERSQTTIPAAIRDALQLKPGELIEYSLLPGGRVIISRQEKEQDDPVISEFLSFLEKDMKKNPQ
HIKSVPTTLWAEVKELTDGVEIDLDAPLTD

Download         Length: 333 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References