Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) HipBST/HipA(toxin)
Location 917160..918490 Replicon chromosome
Accession NZ_CP127389
Organism Proteus sp. HZ0627

Toxin (Protein)


Gene name HipT Uniprot ID -
Locus tag QQS39_RS04215 Protein ID WP_285805444.1
Coordinates 917160..918182 (-) Length 341 a.a.

Antitoxin (Protein)


Gene name HipS Uniprot ID -
Locus tag QQS39_RS04220 Protein ID WP_151434398.1
Coordinates 918179..918490 (-) Length 104 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QQS39_RS04205 (QQS39_04205) 912217..914649 + 2433 WP_285805443.1 ATP-dependent helicase HrpB -
QQS39_RS04210 (QQS39_04210) 914793..917099 + 2307 WP_151434396.1 bifunctional glycosyl transferase/transpeptidase -
QQS39_RS04215 (QQS39_04215) 917160..918182 - 1023 WP_285805444.1 HipA domain-containing protein Toxin
QQS39_RS04220 (QQS39_04220) 918179..918490 - 312 WP_151434398.1 HipA N-terminal domain-containing protein Antitoxin
QQS39_RS04225 (QQS39_04225) 918475..918825 - 351 WP_285805445.1 XRE family transcriptional regulator -
QQS39_RS04230 (QQS39_04230) 919136..920422 - 1287 WP_151434400.1 glutamate-1-semialdehyde 2,1-aminomutase -
QQS39_RS04235 (QQS39_04235) 920698..921042 + 345 WP_006534944.1 iron-sulfur cluster insertion protein ErpA -
QQS39_RS04240 (QQS39_04240) 921756..922274 + 519 WP_285805446.1 Hcp family type VI secretion system effector -
QQS39_RS04245 (QQS39_04245) 922574..923401 - 828 WP_285805447.1 vitamin B12 ABC transporter substrate-binding protein BtuF -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HipA-like, C-terminal

(58-289)

Antitoxin

HipA, N-terminal subdomain 1

(6-98)


Sequences

Toxin        


Download         Length: 341 a.a.        Molecular weight: 38833.72 Da        Isoelectric Point: 5.7401

>T284222 WP_285805444.1 NZ_CP127389:c918182-917160 [Proteus sp. HZ0627]
MNVNNCLINLKELKRSELDSGYSLLGIKSLFNNIDMILNLPFTRSQFIQELPEQQKGMSISGYQPKLSLCVKDNILQVVN
NNGTYILKPSPEEYPYLAENEHATMMVMQRLKFDIPPFGLFRFKQEDGKPEEFAFVIKRYDRIGSDAVRLHQEQLDGAMG
INDKYGLSKGKKTVSYESAAKYLITNIDNSLKNKRDIFLRIVYAYVLGNNDYHLRNMGIILPDNASPSLAPIYDFVSVVP
YPSAFIEYLALPLLALEENDTDTAPGLNSKYGEYIGFDFILLAENIDINLKLAQKWLGDIINSHQLIIDTYNESHMPKEQ
RELVLAYVARRINLLKITTL

Download         Length: 1023 bp

Antitoxin


Download         Length: 104 a.a.        Molecular weight: 12163.97 Da        Isoelectric Point: 5.6505

>AT284222 WP_151434398.1 NZ_CP127389:c918490-918179 [Proteus sp. HZ0627]
MPRKIEVWLYDQPAGVLSEEENGFIFHYYDNYKGRAISLSMPVRKEHYWCEELHPFFKGLAPEGWLRKRYSEIQKIDDKD
LFGLLMNNGNDLLGAVVLREITL

Download         Length: 312 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References