Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/HigB-HigA
Location 4236119..4236709 Replicon chromosome
Accession NZ_CP127378
Organism Xanthomonas fragariae strain LMG 703

Toxin (Protein)


Gene name graT Uniprot ID A0A1Y6HPD3
Locus tag OW158_RS19815 Protein ID WP_002803897.1
Coordinates 4236428..4236709 (-) Length 94 a.a.

Antitoxin (Protein)


Gene name graA Uniprot ID -
Locus tag OW158_RS19810 Protein ID WP_002803896.1
Coordinates 4236119..4236409 (-) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OW158_RS19780 (OW158_19780) 4231624..4232592 - 969 WP_088057082.1 IS5 family transposase -
OW158_RS19785 (OW158_19785) 4232837..4233850 - 1014 WP_082244192.1 hypothetical protein -
OW158_RS19790 (OW158_19790) 4233986..4234633 - 648 WP_088057083.1 transposase -
OW158_RS19795 (OW158_19795) 4234739..4235041 - 303 WP_145954077.1 hypothetical protein -
OW158_RS19800 (OW158_19800) 4235243..4235575 + 333 WP_002803887.1 hypothetical protein -
OW158_RS19805 (OW158_19805) 4235736..4235932 + 197 Protein_3816 hypothetical protein -
OW158_RS19810 (OW158_19810) 4236119..4236409 - 291 WP_002803896.1 HigA family addiction module antitoxin Antitoxin
OW158_RS19815 (OW158_19815) 4236428..4236709 - 282 WP_002803897.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
OW158_RS19820 (OW158_19820) 4237173..4239248 - 2076 WP_065975458.1 exodeoxyribonuclease V subunit alpha -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-1

(7-93)

Antitoxin

Toxin-antitoxin system, antidote protein, HigA

(1-94)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10897.61 Da        Isoelectric Point: 9.7550

>T284214 WP_002803897.1 NZ_CP127378:c4236709-4236428 [Xanthomonas fragariae]
MIKSIVDKEAEKIWVGERSRRLPADIQSVARRKLRMLNAAAHLDDLRIPPANRLEALKGERRGQYSIRINDQLRICFRWM
EGDVAEVEIVDYH

Download         Length: 282 bp

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10528.25 Da        Isoelectric Point: 7.1667

>AT284214 WP_002803896.1 NZ_CP127378:c4236409-4236119 [Xanthomonas fragariae]
MTVLPNIHPGEILLEEFLEPMGISQNALARATGVPPRRINEIVLGKRGITADTAVRLAAALCTTERFWLGLQADYELEQA
HRALGDLPSRIKRLAA

Download         Length: 291 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1Y6HPD3

Antitoxin

Source ID Structure

References