Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/HigB-HigA
Location 4236119..4236709 Replicon chromosome
Accession NZ_CP127378
Organism Xanthomonas fragariae strain LMG 703

Toxin (Protein)


Gene name graT Uniprot ID A0A1Y6HPD3
Locus tag OW158_RS19815 Protein ID WP_002803897.1
Coordinates 4236428..4236709 (-) Length 94 a.a.

Antitoxin (Protein)


Gene name graA Uniprot ID -
Locus tag OW158_RS19810 Protein ID WP_002803896.1
Coordinates 4236119..4236409 (-) Length 97 a.a.

Genomic Context

OW158_RS19800OW158_RS19805OW158_RS19780OW158_RS19785OW158_RS19790OW158_RS19795OW158_RS19810OW158_RS19815OW158_RS19820
Location: 4235243..4235575 (333 bp)
Type: Others
Protein ID: WP_002803887.1
Location: 4235736..4235932 (197 bp)
Type: Others
Protein ID: Protein_3816
Location: 4231624..4232592 (969 bp)
Type: Others
Protein ID: WP_088057082.1
Location: 4232837..4233850 (1014 bp)
Type: Others
Protein ID: WP_082244192.1
Location: 4233986..4234633 (648 bp)
Type: Others
Protein ID: WP_088057083.1
Location: 4234739..4235041 (303 bp)
Type: Others
Protein ID: WP_145954077.1
Location: 4236119..4236409 (291 bp)
Type: Antitoxin
Protein ID: WP_002803896.1
Location: 4236428..4236709 (282 bp)
Type: Toxin
Protein ID: WP_002803897.1
Location: 4237173..4239248 (2076 bp)
Type: Others
Protein ID: WP_065975458.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
OW158_RS19780 (OW158_19780)4231624..4232592-969WP_088057082.1IS5 family transposase-
OW158_RS19785 (OW158_19785)4232837..4233850-1014WP_082244192.1hypothetical protein-
OW158_RS19790 (OW158_19790)4233986..4234633-648WP_088057083.1transposase-
OW158_RS19795 (OW158_19795)4234739..4235041-303WP_145954077.1hypothetical protein-
OW158_RS19800 (OW158_19800)4235243..4235575+333WP_002803887.1hypothetical protein-
OW158_RS19805 (OW158_19805)4235736..4235932+197Protein_3816hypothetical protein-
OW158_RS19810 (OW158_19810)4236119..4236409-291WP_002803896.1HigA family addiction module antitoxinAntitoxin
OW158_RS19815 (OW158_19815)4236428..4236709-282WP_002803897.1type II toxin-antitoxin system RelE/ParE family toxinToxin
OW158_RS19820 (OW158_19820)4237173..4239248-2076WP_065975458.1exodeoxyribonuclease V subunit alpha-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-1

(7-93)

Antitoxin

Toxin-antitoxin system, antidote protein, HigA

(1-94)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10897.61 Da        Isoelectric Point: 9.7550

>T284214 WP_002803897.1 NZ_CP127378:c4236709-4236428 [Xanthomonas fragariae]
MIKSIVDKEAEKIWVGERSRRLPADIQSVARRKLRMLNAAAHLDDLRIPPANRLEALKGERRGQYSIRINDQLRICFRWM
EGDVAEVEIVDYH

Download         Length: 282 bp

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10528.25 Da        Isoelectric Point: 7.1667

>AT284214 WP_002803896.1 NZ_CP127378:c4236409-4236119 [Xanthomonas fragariae]
MTVLPNIHPGEILLEEFLEPMGISQNALARATGVPPRRINEIVLGKRGITADTAVRLAAALCTTERFWLGLQADYELEQA
HRALGDLPSRIKRLAA

Download         Length: 291 bp


Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBA0A1Y6HPD3

Antitoxin

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Source
ID
Structure
No matching records found

References