Detailed information of TA system TA284127

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): ldrD-rdlD/Ldr(toxin)
• Location: 4184241..4184461
• Replicon: chromosome
• Accession: NZ_CP127306
• Organism: Escherichia coli strain C51

Toxin (Protein)

• Gene name: ldrD
• Uniprot ID: B7LGX8
• Locus tag: QRM70_RS20395
• Protein ID: WP_000170965.1
• Coordinates: 4184354..4184461 (+)
• Length: 36 a.a.

Antitoxin (RNA)

Gene name	rdlD
Locus tag	-
Coordinates	4184241..4184307 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
QRM70_RS20370	4179520..4180914	-	1395	WP_000086201.1	inverse autotransporter invasin YchO	-
QRM70_RS20375	4181099..4181452	+	354	WP_001169669.1	DsrE/F sulfur relay family protein YchN	-
QRM70_RS20380	4181496..4182191	-	696	WP_001297117.1	glutathione-specific gamma-glutamylcyclotransferase	-
QRM70_RS20385	4182349..4182579	-	231	WP_001146442.1	putative cation transport regulator ChaB	-
QRM70_RS20390	4182849..4183949	+	1101	WP_001295620.1	sodium-potassium/proton antiporter ChaA	-
-	4184241..4184307	-	67	-	-	Antitoxin
QRM70_RS20395	4184354..4184461	+	108	WP_000170965.1	type I toxin-antitoxin system toxin Ldr family protein	Toxin
-	4184774..4184837	-	64	NuclAT_33	-	-
-	4184774..4184837	-	64	NuclAT_33	-	-
-	4184774..4184837	-	64	NuclAT_33	-	-
-	4184774..4184837	-	64	NuclAT_33	-	-
-	4184774..4184837	-	64	NuclAT_36	-	-
-	4184774..4184837	-	64	NuclAT_36	-	-
-	4184774..4184837	-	64	NuclAT_36	-	-
-	4184774..4184837	-	64	NuclAT_36	-	-
-	4184774..4184837	-	64	NuclAT_39	-	-
-	4184774..4184837	-	64	NuclAT_39	-	-
-	4184774..4184837	-	64	NuclAT_39	-	-
-	4184774..4184837	-	64	NuclAT_39	-	-
-	4184774..4184837	-	64	NuclAT_42	-	-
-	4184774..4184837	-	64	NuclAT_42	-	-
-	4184774..4184837	-	64	NuclAT_42	-	-
-	4184774..4184837	-	64	NuclAT_42	-	-
-	4184774..4184837	-	64	NuclAT_45	-	-
-	4184774..4184837	-	64	NuclAT_45	-	-
-	4184774..4184837	-	64	NuclAT_45	-	-
-	4184774..4184837	-	64	NuclAT_45	-	-
-	4184774..4184837	-	64	NuclAT_48	-	-
-	4184774..4184837	-	64	NuclAT_48	-	-
-	4184774..4184837	-	64	NuclAT_48	-	-
-	4184774..4184837	-	64	NuclAT_48	-	-
-	4184775..4184837	-	63	NuclAT_50	-	-
-	4184775..4184837	-	63	NuclAT_50	-	-
-	4184775..4184837	-	63	NuclAT_50	-	-
-	4184775..4184837	-	63	NuclAT_50	-	-
-	4184775..4184837	-	63	NuclAT_53	-	-
-	4184775..4184837	-	63	NuclAT_53	-	-
-	4184775..4184837	-	63	NuclAT_53	-	-
-	4184775..4184837	-	63	NuclAT_53	-	-
-	4184775..4184837	-	63	NuclAT_56	-	-
-	4184775..4184837	-	63	NuclAT_56	-	-
-	4184775..4184837	-	63	NuclAT_56	-	-
-	4184775..4184837	-	63	NuclAT_56	-	-
-	4184776..4184837	-	62	NuclAT_15	-	-
-	4184776..4184837	-	62	NuclAT_15	-	-
-	4184776..4184837	-	62	NuclAT_15	-	-
-	4184776..4184837	-	62	NuclAT_15	-	-
-	4184776..4184837	-	62	NuclAT_18	-	-
-	4184776..4184837	-	62	NuclAT_18	-	-
-	4184776..4184837	-	62	NuclAT_18	-	-
-	4184776..4184837	-	62	NuclAT_18	-	-
-	4184776..4184837	-	62	NuclAT_21	-	-
-	4184776..4184837	-	62	NuclAT_21	-	-
-	4184776..4184837	-	62	NuclAT_21	-	-
-	4184776..4184837	-	62	NuclAT_21	-	-
-	4184776..4184837	-	62	NuclAT_24	-	-
-	4184776..4184837	-	62	NuclAT_24	-	-
-	4184776..4184837	-	62	NuclAT_24	-	-
-	4184776..4184837	-	62	NuclAT_24	-	-
-	4184776..4184837	-	62	NuclAT_27	-	-
-	4184776..4184837	-	62	NuclAT_27	-	-
-	4184776..4184837	-	62	NuclAT_27	-	-
-	4184776..4184837	-	62	NuclAT_27	-	-
-	4184776..4184837	-	62	NuclAT_30	-	-
-	4184776..4184837	-	62	NuclAT_30	-	-
-	4184776..4184837	-	62	NuclAT_30	-	-
-	4184776..4184837	-	62	NuclAT_30	-	-
QRM70_RS20400	4184890..4184997	+	108	WP_000170926.1	type I toxin-antitoxin system toxin Ldr family protein	-
-	4185310..4185375	-	66	NuclAT_32	-	-
-	4185310..4185375	-	66	NuclAT_32	-	-
-	4185310..4185375	-	66	NuclAT_32	-	-
-	4185310..4185375	-	66	NuclAT_32	-	-
-	4185310..4185375	-	66	NuclAT_35	-	-
-	4185310..4185375	-	66	NuclAT_35	-	-
-	4185310..4185375	-	66	NuclAT_35	-	-
-	4185310..4185375	-	66	NuclAT_35	-	-
-	4185310..4185375	-	66	NuclAT_38	-	-
-	4185310..4185375	-	66	NuclAT_38	-	-
-	4185310..4185375	-	66	NuclAT_38	-	-
-	4185310..4185375	-	66	NuclAT_38	-	-
-	4185310..4185375	-	66	NuclAT_41	-	-
-	4185310..4185375	-	66	NuclAT_41	-	-
-	4185310..4185375	-	66	NuclAT_41	-	-
-	4185310..4185375	-	66	NuclAT_41	-	-
-	4185310..4185375	-	66	NuclAT_44	-	-
-	4185310..4185375	-	66	NuclAT_44	-	-
-	4185310..4185375	-	66	NuclAT_44	-	-
-	4185310..4185375	-	66	NuclAT_44	-	-
-	4185310..4185375	-	66	NuclAT_47	-	-
-	4185310..4185375	-	66	NuclAT_47	-	-
-	4185310..4185375	-	66	NuclAT_47	-	-
-	4185310..4185375	-	66	NuclAT_47	-	-
-	4185311..4185377	-	67	NuclAT_49	-	-
-	4185311..4185377	-	67	NuclAT_49	-	-
-	4185311..4185377	-	67	NuclAT_49	-	-
-	4185311..4185377	-	67	NuclAT_49	-	-
-	4185311..4185377	-	67	NuclAT_52	-	-
-	4185311..4185377	-	67	NuclAT_52	-	-
-	4185311..4185377	-	67	NuclAT_52	-	-
-	4185311..4185377	-	67	NuclAT_52	-	-
-	4185311..4185377	-	67	NuclAT_55	-	-
-	4185311..4185377	-	67	NuclAT_55	-	-
-	4185311..4185377	-	67	NuclAT_55	-	-
-	4185311..4185377	-	67	NuclAT_55	-	-
-	4185312..4185375	-	64	NuclAT_14	-	-
-	4185312..4185375	-	64	NuclAT_14	-	-
-	4185312..4185375	-	64	NuclAT_14	-	-
-	4185312..4185375	-	64	NuclAT_14	-	-
-	4185312..4185375	-	64	NuclAT_17	-	-
-	4185312..4185375	-	64	NuclAT_17	-	-
-	4185312..4185375	-	64	NuclAT_17	-	-
-	4185312..4185375	-	64	NuclAT_17	-	-
-	4185312..4185375	-	64	NuclAT_20	-	-
-	4185312..4185375	-	64	NuclAT_20	-	-
-	4185312..4185375	-	64	NuclAT_20	-	-
-	4185312..4185375	-	64	NuclAT_20	-	-
-	4185312..4185375	-	64	NuclAT_23	-	-
-	4185312..4185375	-	64	NuclAT_23	-	-
-	4185312..4185375	-	64	NuclAT_23	-	-
-	4185312..4185375	-	64	NuclAT_23	-	-
-	4185312..4185375	-	64	NuclAT_26	-	-
-	4185312..4185375	-	64	NuclAT_26	-	-
-	4185312..4185375	-	64	NuclAT_26	-	-
-	4185312..4185375	-	64	NuclAT_26	-	-
-	4185312..4185375	-	64	NuclAT_29	-	-
-	4185312..4185375	-	64	NuclAT_29	-	-
-	4185312..4185375	-	64	NuclAT_29	-	-
-	4185312..4185375	-	64	NuclAT_29	-	-
QRM70_RS20405	4185425..4185532	+	108	WP_000170954.1	type I toxin-antitoxin system toxin Ldr family protein	-
QRM70_RS20410	4185681..4186535	-	855	WP_000811065.1	3-deoxy-8-phosphooctulonate synthase	-
QRM70_RS20415	4186571..4187380	-	810	WP_001257044.1	invasion regulator SirB1	-
QRM70_RS20420	4187384..4187776	-	393	WP_000200392.1	invasion regulator SirB2	-
QRM70_RS20425	4187773..4188606	-	834	WP_000456467.1	peptide chain release factor N(5)-glutamine methyltransferase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Type I toxin-antitoxin system, toxin Ldr (1-35)

Sequences

Toxin

Protein

• Length: 36 a.a.
• Molecular weight: 4001.77 Da
• Isoelectric Point: 11.4779

>T284127 WP_000170965.1 NZ_CP127306:4184354-4184461 [Escherichia coli]
MTLAQFAMTFWHDLAAPILAGIITAAIVSWWRNRK

Nucleotide

• Length: 108 bp

Antitoxin

Nucleotide

• Length: 67 bp

>AT284127 NZ_CP127306:c4184307-4184241 [Escherichia coli]
TGTCTGGTTTCAAGATTAGCCCCCGTTCTGTTGTCAGGTTTTACCTCTCAACGTGCGGGGGTTTTCT

Structures

Toxin

• AlphaFold DB: A0A0E0Y029

Antitoxin