Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | higBA (relBE)/HigB-HigA |
Location | 4794170..4794741 | Replicon | chromosome |
Accession | NC_018691 | ||
Organism | Alcanivorax dieselolei B5 |
Toxin (Protein)
Gene name | higB | Uniprot ID | A0A154C0S4 |
Locus tag | B5T_RS21485 | Protein ID | WP_026948751.1 |
Coordinates | 4794170..4794448 (+) | Length | 93 a.a. |
Antitoxin (Protein)
Gene name | graA | Uniprot ID | - |
Locus tag | B5T_RS21490 | Protein ID | WP_014996637.1 |
Coordinates | 4794448..4794741 (+) | Length | 98 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
B5T_RS21460 | 4789177..4789986 | - | 810 | WP_014996631.1 | mechanosensitive ion channel | - |
B5T_RS21465 | 4790138..4790614 | - | 477 | WP_014996632.1 | peroxiredoxin | - |
B5T_RS21470 | 4790814..4792829 | - | 2016 | WP_202803088.1 | VIT and VWA domain-containing protein | - |
B5T_RS21475 | 4793017..4793532 | - | 516 | WP_014996634.1 | hypothetical protein | - |
B5T_RS21480 | 4793563..4794048 | - | 486 | WP_014996635.1 | YajQ family cyclic di-GMP-binding protein | - |
B5T_RS21485 | 4794170..4794448 | + | 279 | WP_026948751.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
B5T_RS21490 | 4794448..4794741 | + | 294 | WP_014996637.1 | HigA family addiction module antidote protein | Antitoxin |
B5T_RS21495 | 4794837..4795436 | + | 600 | WP_014996638.1 | tRNA (pseudouridine(54)-N(1))-methyltransferase TrmY | - |
B5T_RS21500 | 4795455..4796120 | - | 666 | WP_014996639.1 | thiopurine S-methyltransferase | - |
B5T_RS21505 | 4796189..4798954 | - | 2766 | WP_014996640.1 | DNA polymerase I | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 93 a.a. Molecular weight: 10532.07 Da Isoelectric Point: 10.5861
>T28389 WP_026948751.1 NC_018691:4794170-4794448 [Alcanivorax dieselolei B5]
MIKSFRHKGLQRFFTTGSTAGVQTTHAKRLRMQLAALDTATVIEDMDIPGFSLHPLKGKAKGRWSIRVSGNWRLTFEFKD
GNAYVLNYEDYH
MIKSFRHKGLQRFFTTGSTAGVQTTHAKRLRMQLAALDTATVIEDMDIPGFSLHPLKGKAKGRWSIRVSGNWRLTFEFKD
GNAYVLNYEDYH
Download Length: 279 bp
>T28389 NC_018691:4794170-4794448 [Alcanivorax dieselolei B5]
ATGATCAAATCATTCCGCCACAAAGGACTGCAGCGGTTTTTCACCACCGGCTCCACCGCCGGTGTTCAAACCACTCATGC
CAAGCGTCTGAGGATGCAACTGGCCGCCCTGGATACCGCAACGGTCATTGAGGATATGGATATCCCGGGCTTCTCCTTGC
ACCCCTTGAAAGGAAAAGCAAAGGGGCGCTGGTCCATCCGGGTAAGCGGAAACTGGCGTCTGACCTTTGAATTCAAGGAC
GGCAACGCCTATGTGTTGAACTACGAGGATTATCACTGA
ATGATCAAATCATTCCGCCACAAAGGACTGCAGCGGTTTTTCACCACCGGCTCCACCGCCGGTGTTCAAACCACTCATGC
CAAGCGTCTGAGGATGCAACTGGCCGCCCTGGATACCGCAACGGTCATTGAGGATATGGATATCCCGGGCTTCTCCTTGC
ACCCCTTGAAAGGAAAAGCAAAGGGGCGCTGGTCCATCCGGGTAAGCGGAAACTGGCGTCTGACCTTTGAATTCAAGGAC
GGCAACGCCTATGTGTTGAACTACGAGGATTATCACTGA
Antitoxin
Download Length: 98 a.a. Molecular weight: 10827.49 Da Isoelectric Point: 8.6425
>AT28389 WP_014996637.1 NC_018691:4794448-4794741 [Alcanivorax dieselolei B5]
MNMHHPPHPGEFIREVYLEPHGLSVRALAAKLDISPSSLSRVLNGASGVSPEMALRLSKALGRTPESWLALQDLYDLWQA
RQRINLDKVQAIDFKVA
MNMHHPPHPGEFIREVYLEPHGLSVRALAAKLDISPSSLSRVLNGASGVSPEMALRLSKALGRTPESWLALQDLYDLWQA
RQRINLDKVQAIDFKVA
Download Length: 294 bp
>AT28389 NC_018691:4794448-4794741 [Alcanivorax dieselolei B5]
ATGAACATGCACCATCCCCCACACCCCGGTGAGTTCATCCGAGAGGTCTACCTGGAACCTCACGGTTTAAGTGTGCGTGC
GCTGGCGGCAAAGCTGGATATCTCTCCCTCCTCGCTCAGTCGCGTCCTTAACGGGGCCAGCGGCGTGAGCCCGGAAATGG
CTTTGCGCCTATCAAAAGCCCTGGGGCGAACTCCGGAAAGCTGGCTGGCCTTGCAGGACCTTTACGACCTCTGGCAGGCA
CGGCAACGGATCAATCTGGACAAGGTCCAGGCCATCGATTTCAAGGTTGCCTGA
ATGAACATGCACCATCCCCCACACCCCGGTGAGTTCATCCGAGAGGTCTACCTGGAACCTCACGGTTTAAGTGTGCGTGC
GCTGGCGGCAAAGCTGGATATCTCTCCCTCCTCGCTCAGTCGCGTCCTTAACGGGGCCAGCGGCGTGAGCCCGGAAATGG
CTTTGCGCCTATCAAAAGCCCTGGGGCGAACTCCGGAAAGCTGGCTGGCCTTGCAGGACCTTTACGACCTCTGGCAGGCA
CGGCAACGGATCAATCTGGACAAGGTCCAGGCCATCGATTTCAAGGTTGCCTGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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