Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/Txe-RelB
Location 231676..232199 Replicon chromosome
Accession NZ_CP127101
Organism Staphylococcus pseudintermedius strain 10916-77753

Toxin (Protein)


Gene name yoeB Uniprot ID A0A8H9EQJ3
Locus tag QQZ06_RS01030 Protein ID WP_014612815.1
Coordinates 231933..232199 (+) Length 89 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID A0A3D8YKM0
Locus tag QQZ06_RS01025 Protein ID WP_014612814.1
Coordinates 231676..231933 (+) Length 86 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QQZ06_RS01015 (QQZ06_01015) 228824..229318 - 495 WP_015729749.1 isoprenylcysteine carboxylmethyltransferase family protein -
QQZ06_RS01020 (QQZ06_01020) 229578..231482 + 1905 WP_214561763.1 triacylglycerol lipase -
QQZ06_RS01025 (QQZ06_01025) 231676..231933 + 258 WP_014612814.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
QQZ06_RS01030 (QQZ06_01030) 231933..232199 + 267 WP_014612815.1 Txe/YoeB family addiction module toxin Toxin
QQZ06_RS01035 (QQZ06_01035) 232560..232661 - 102 WP_019169745.1 SE2200 family small protein -
QQZ06_RS01040 (QQZ06_01040) 232675..234168 - 1494 WP_014612817.1 L-lactate dehydrogenase (quinone) -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(5-87)

Antitoxin

(1-68)


Sequences


Toxin        


Download         Length: 89 a.a.        Molecular weight: 10555.15 Da        Isoelectric Point: 10.2281

>T283563 WP_014612815.1 NZ_CP127101:231933-232199 [Staphylococcus pseudintermedius]
MGNYSVLIKNSAKNDLKKIKKSLLKEQFSKIIEVLKINPYEASQSFEKLQPKHSARYLRRLNHQHRVVYTVDDEKREVYI
FSAWSHYE

Download         Length: 267 bp


Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9866.87 Da        Isoelectric Point: 4.1100

>AT283563 WP_014612814.1 NZ_CP127101:231676-231933 [Staphylococcus pseudintermedius]
MIIKTPTNARKEFYELLKQVNDNHEPIIISGSKSENNAVIVSQEDWDSIQETLFLEYTGTMDKVRAREKDDSGYTNIDDI
DWDNL

Download         Length: 258 bp


Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure
AlphaFold DB A0A3D8YKM0

References