283560

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/Txe-RelB
Location 227490..228013 Replicon chromosome
Accession NZ_CP127100
Organism Staphylococcus pseudintermedius strain 6127-64107

Toxin (Protein)


Gene name yoeB Uniprot ID A0A317Z6J3
Locus tag QQZ05_RS01015 Protein ID WP_037542127.1
Coordinates 227747..228013 (+) Length 89 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID A0A2P5PI69
Locus tag QQZ05_RS01010 Protein ID WP_015729747.1
Coordinates 227490..227747 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QQZ05_RS00995 (QQZ05_00995) 223538..224326 + 789 WP_063284837.1 arylamine N-acetyltransferase -
QQZ05_RS01000 (QQZ05_01000) 224638..225132 - 495 WP_015729749.1 isoprenylcysteine carboxylmethyltransferase family protein -
QQZ05_RS01005 (QQZ05_01005) 225392..227296 + 1905 WP_285534310.1 triacylglycerol lipase -
QQZ05_RS01010 (QQZ05_01010) 227490..227747 + 258 WP_015729747.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
QQZ05_RS01015 (QQZ05_01015) 227747..228013 + 267 WP_037542127.1 Txe/YoeB family addiction module toxin Toxin
QQZ05_RS01020 (QQZ05_01020) 228364..228465 - 102 WP_019169745.1 SE2200 family small protein -
QQZ05_RS01025 (QQZ05_01025) 228479..229972 - 1494 WP_014612817.1 L-lactate dehydrogenase (quinone) -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(9-87)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-68)


Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10555.10 Da        Isoelectric Point: 10.1602

>T283560 WP_037542127.1 NZ_CP127100:227747-228013 [Staphylococcus pseudintermedius]
MGNYSVLIKNSAKNDLKKIKKSLLKEQFSKIIEVLKINPYEASQSFEKLQPKHSARYSRRLNHQHRVVYTVDDEKREVYI
FSAWSYYE

Download         Length: 267 bp

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9836.85 Da        Isoelectric Point: 4.1100

>AT283560 WP_015729747.1 NZ_CP127100:227490-227747 [Staphylococcus pseudintermedius]
MIIKTPTNARKEFYELLKQVNDNHEPIIISGSKSENNAVIVSQEDWDGIQETLFLEYTGTMDKVRAREKDDSGYTNIDDI
DWDNL

Download         Length: 258 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A317Z6J3

Antitoxin

Source ID Structure
AlphaFold DB A0A2P5PI69

References