Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/Txe-RelB
Location 247114..247637 Replicon chromosome
Accession NZ_CP127094
Organism Staphylococcus pseudintermedius strain 19KM0990

Toxin (Protein)


Gene name yoeB Uniprot ID A0A8H9EQJ3
Locus tag QQO15_RS01095 Protein ID WP_014612815.1
Coordinates 247371..247637 (+) Length 89 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID A0A3D8YKM0
Locus tag QQO15_RS01090 Protein ID WP_014612814.1
Coordinates 247114..247371 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QQO15_RS01075 (QQO15_01075) 243162..243968 + 807 WP_140237858.1 arylamine N-acetyltransferase -
QQO15_RS01080 (QQO15_01080) 244262..244756 - 495 WP_037542124.1 isoprenylcysteine carboxylmethyltransferase family protein -
QQO15_RS01085 (QQO15_01085) 245016..246920 + 1905 WP_190320772.1 triacylglycerol lipase -
QQO15_RS01090 (QQO15_01090) 247114..247371 + 258 WP_014612814.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
QQO15_RS01095 (QQO15_01095) 247371..247637 + 267 WP_014612815.1 Txe/YoeB family addiction module toxin Toxin
QQO15_RS01100 (QQO15_01100) 247981..248082 - 102 WP_019169745.1 SE2200 family small protein -
QQO15_RS01105 (QQO15_01105) 248096..249589 - 1494 WP_014612817.1 L-lactate dehydrogenase (quinone) -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-87)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-68)


Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10555.15 Da        Isoelectric Point: 10.2281

>T283550 WP_014612815.1 NZ_CP127094:247371-247637 [Staphylococcus pseudintermedius]
MGNYSVLIKNSAKNDLKKIKKSLLKEQFSKIIEVLKINPYEASQSFEKLQPKHSARYLRRLNHQHRVVYTVDDEKREVYI
FSAWSHYE

Download         Length: 267 bp

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9866.87 Da        Isoelectric Point: 4.1100

>AT283550 WP_014612814.1 NZ_CP127094:247114-247371 [Staphylococcus pseudintermedius]
MIIKTPTNARKEFYELLKQVNDNHEPIIISGSKSENNAVIVSQEDWDSIQETLFLEYTGTMDKVRAREKDDSGYTNIDDI
DWDNL

Download         Length: 258 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A3D8YKM0

References