Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2418744..2419023 Replicon chromosome
Accession NZ_CP127021
Organism Staphylococcus aureus strain CC239-MRSA-III(var.) isolate Trinidad&Tobago_2020-021_7037M

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag QQO10_RS12290 Protein ID WP_001802298.1
Coordinates 2418919..2419023 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF3
Locus tag -
Coordinates 2418744..2418923 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QQO10_RS12265 (QQO10_12265) 2414943..2415608 - 666 WP_001024094.1 SDR family oxidoreductase -
QQO10_RS12270 (QQO10_12270) 2415760..2416080 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
QQO10_RS12275 (QQO10_12275) 2416082..2417062 + 981 WP_000019744.1 CDF family zinc efflux transporter CzrB -
QQO10_RS12280 (QQO10_12280) 2417328..2418419 + 1092 WP_000495671.1 lytic regulatory protein -
- 2418744..2418923 + 180 - - Antitoxin
QQO10_RS12290 (QQO10_12290) 2418919..2419023 - 105 WP_001802298.1 hypothetical protein Toxin
QQO10_RS12295 (QQO10_12295) 2419184..2419667 - 484 Protein_2387 recombinase family protein -
QQO10_RS12300 (QQO10_12300) 2419710..2420846 - 1137 WP_000115564.1 SAP domain-containing protein -
QQO10_RS12305 (QQO10_12305) 2421135..2421227 + 93 WP_001790138.1 hypothetical protein -
QQO10_RS12310 (QQO10_12310) 2421932..2422789 - 858 WP_000370924.1 HAD family hydrolase -
QQO10_RS12315 (QQO10_12315) 2422857..2423639 - 783 WP_000908176.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T283525 WP_001802298.1 NZ_CP127021:c2419023-2418919 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

Antitoxin


Download         Length: 180 bp

>AT283525 NZ_CP127021:2418744-2418923 [Staphylococcus aureus]
GTGTTAAAATATATTTGTAGTAAGTAGAAGCAAAAGATGAAAATCATTAACTCTTGAAACACAAAAAGGGCAACACTCGG
AAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAAATGCCGGTC
AAAGCGAATAGAAGGTTATT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References