Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/HigB-HigA
Location 1694307..1694923 Replicon chromosome
Accession NZ_CP126994
Organism Acidisoma sp. PAMC 29798

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag QP803_RS08110 Protein ID WP_284947264.1
Coordinates 1694307..1694603 (+) Length 99 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag QP803_RS08115 Protein ID WP_284947265.1
Coordinates 1694615..1694923 (+) Length 103 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QP803_RS08100 1690543..1691262 - 720 WP_284947262.1 hypothetical protein -
QP803_RS08105 1691919..1694039 + 2121 WP_284947263.1 DUF3363 domain-containing protein -
QP803_RS08110 1694307..1694603 + 297 WP_284947264.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
QP803_RS08115 1694615..1694923 + 309 WP_284947265.1 HigA family addiction module antitoxin Antitoxin
QP803_RS08120 1695053..1695301 + 249 WP_284947266.1 hypothetical protein -
QP803_RS08125 1695323..1696396 + 1074 Protein_1608 recombinase family protein -
QP803_RS08130 1696538..1696783 - 246 WP_284947267.1 hypothetical protein -
QP803_RS08140 1697072..1697674 - 603 WP_284947268.1 DUF1684 domain-containing protein -
QP803_RS08145 1697741..1699165 - 1425 WP_284947269.1 sensor domain-containing diguanylate cyclase -
QP803_RS08150 1699316..1699777 - 462 WP_284947270.1 CreA family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-1

(4-95)

Antitoxin

Toxin-antitoxin system, antidote protein, HigA

(1-95)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11714.15 Da        Isoelectric Point: 6.0778

>T283475 WP_284947264.1 NZ_CP126994:1694307-1694603 [Acidisoma sp. PAMC 29798]
MIVGFRDEWLHAFFVDDVRSRNIPPDLEARLFRKLQMIDDATTDQDLRVPPSNHFEKLRGNLAEFHSIRVNQQWRLIFRW
DGGRGEAADIYLDDHSYR

Download         Length: 297 bp

Antitoxin


Download         Length: 103 a.a.        Molecular weight: 11587.41 Da        Isoelectric Point: 10.1816

>AT283475 WP_284947265.1 NZ_CP126994:1694615-1694923 [Acidisoma sp. PAMC 29798]
MLTTKRKPATVGEILTEEFMEPMGLTQAALAEAMGVQRKHVNELCNDRRNVTAATALILARVFGNSPDFWLNVQRRSDLW
DAMHIPKERERIERARPLKSAA

Download         Length: 309 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References