283465

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) higBA (relBE)/HigB-HigA
Location 63745..64338 Replicon chromosome
Accession NZ_CP126992
Organism Pseudomonas syringae pv. antirrhini str. 126

Toxin (Protein)


Gene name graT Uniprot ID -
Locus tag QQF68_RS00320 Protein ID WP_081025557.1
Coordinates 63745..64023 (+) Length 93 a.a.

Antitoxin (Protein)


Gene name graA Uniprot ID Q88B19
Locus tag QQF68_RS00325 Protein ID WP_005739893.1
Coordinates 64033..64338 (+) Length 102 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QQF68_RS00300 (QQF68_00300) 59007..60245 - 1239 WP_057419370.1 diaminopimelate decarboxylase -
QQF68_RS00305 (QQF68_00305) 60247..61122 - 876 WP_011103032.1 DMT family transporter -
QQF68_RS00310 (QQF68_00310) 61122..62405 - 1284 WP_057419369.1 lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family protein -
QQF68_RS00315 (QQF68_00315) 62560..63495 + 936 WP_005739904.1 LysR family transcriptional regulator -
QQF68_RS00320 (QQF68_00320) 63745..64023 + 279 WP_081025557.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
QQF68_RS00325 (QQF68_00325) 64033..64338 + 306 WP_005739893.1 HigA family addiction module antitoxin Antitoxin
QQF68_RS00330 (QQF68_00330) 64372..64653 - 282 WP_007246531.1 accessory factor UbiK family protein -
QQF68_RS00335 (QQF68_00335) 65073..65411 + 339 WP_002555808.1 P-II family nitrogen regulator -
QQF68_RS00340 (QQF68_00340) 65447..66784 + 1338 WP_005739890.1 ammonium transporter -
QQF68_RS00345 (QQF68_00345) 67027..67452 + 426 WP_005768513.1 secondary thiamine-phosphate synthase enzyme YjbQ -
QQF68_RS00350 (QQF68_00350) 67551..67883 + 333 WP_007246533.1 transcriptional regulator SutA -
QQF68_RS00355 (QQF68_00355) 67958..68650 - 693 WP_057419367.1 HAD family hydrolase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(6-92)

Antitoxin

(6-84)


Sequences


Toxin        


Download         Length: 93 a.a.        Molecular weight: 10461.09 Da        Isoelectric Point: 9.1475

>T283465 WP_081025557.1 NZ_CP126992:63745-64023 [Pseudomonas syringae pv. antirrhini str. 126]
MIVSFKCVNTRYLFLQGKTRLWPSIKSVAERKLAMLDAATSILDLRSPPGNRLEALDGSRSGQYSVRINAQFRICFVWSI
NGPEDVEIVDYH

Download         Length: 279 bp


Antitoxin


Download         Length: 102 a.a.        Molecular weight: 11158.01 Da        Isoelectric Point: 7.7509

>AT283465 WP_005739893.1 NZ_CP126992:64033-64338 [Pseudomonas syringae pv. antirrhini str. 126]
MNKNGMRPVHPGEVLKEEYLEPMGLTAAALARALKVSTPTVNDIVLQRRGVSADVALRLAVCLETSPEFWLNLQLAYDLR
KAETEKGAQIREQVKCLAHCA

Download         Length: 306 bp


Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure
AlphaFold DB A0A0K8LYY6

References