Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/RelE-HTH
Location 685451..686094 Replicon chromosome
Accession NZ_CP126977
Organism Gallibacterium anatis strain DFSO2

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag QP020_RS03285 Protein ID WP_285098898.1
Coordinates 685451..685795 (+) Length 115 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag QP020_RS03290 Protein ID WP_285098900.1
Coordinates 685798..686094 (+) Length 99 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QP020_RS03255 (QP020_03255) 680659..680871 + 213 WP_039149120.1 TraR/DksA C4-type zinc finger protein -
QP020_RS03260 (QP020_03260) 680868..681359 + 492 WP_013745052.1 phage tail protein -
QP020_RS03265 (QP020_03265) 681347..681799 + 453 WP_039149117.1 phage virion morphogenesis protein -
QP020_RS03270 (QP020_03270) 681788..682168 - 381 WP_285098894.1 hypothetical protein -
QP020_RS03275 (QP020_03275) 682174..682455 - 282 WP_285098895.1 hypothetical protein -
QP020_RS03280 (QP020_03280) 682534..685377 + 2844 WP_285098896.1 phage tail tape measure protein -
QP020_RS03285 (QP020_03285) 685451..685795 + 345 WP_285098898.1 hypothetical protein Toxin
QP020_RS03290 (QP020_03290) 685798..686094 + 297 WP_285098900.1 NadS family protein Antitoxin
QP020_RS03295 (QP020_03295) 686215..686841 + 627 WP_039146340.1 phage baseplate assembly protein V -
QP020_RS03300 (QP020_03300) 686838..687170 + 333 WP_285098901.1 GPW/gp25 family protein -
QP020_RS03305 (QP020_03305) 687171..688082 + 912 WP_285098902.1 baseplate J/gp47 family protein -
QP020_RS03310 (QP020_03310) 688075..688614 + 540 WP_285098904.1 phage tail protein I -
QP020_RS03315 (QP020_03315) 688633..690483 + 1851 WP_285098906.1 phage tail protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 669654..713607 43953


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(39-82)


Sequences

Toxin        


Download         Length: 115 a.a.        Molecular weight: 13045.03 Da        Isoelectric Point: 7.9955

>T283435 WP_285098898.1 NZ_CP126977:685451-685795 [Gallibacterium anatis]
MNTDKLITFIETPIFEEDRKALLSDEEYQAFQAYMLDNFHLGDFIQHTGGCQKIRWKLSGNNKGKSGGVRIIYYSLTAKG
KLYLLMMYPKSEKDNMNAAEKAILKSIVDQLKGD

Download         Length: 345 bp

Antitoxin


Download         Length: 99 a.a.        Molecular weight: 11072.93 Da        Isoelectric Point: 10.3121

>AT283435 WP_285098900.1 NZ_CP126977:685798-686094 [Gallibacterium anatis]
MDKKLFDRLVKSAEQMVAIEKGEMQPAPHTVTTFRIPDVKKIRANTHLKQNEFADLLGVSTALVQSWETARRVPNGPALK
LLNIIEQQPQIIDTLRAI

Download         Length: 297 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References