Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/RelE-HTH
Location 705510..706153 Replicon chromosome
Accession NZ_CP126975
Organism Gallibacterium anatis strain BJF12

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag QP018_RS03430 Protein ID WP_285091016.1
Coordinates 705510..705854 (+) Length 115 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag QP018_RS03435 Protein ID WP_039094358.1
Coordinates 705857..706153 (+) Length 99 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QP018_RS03405 (QP018_03405) 700711..701202 + 492 WP_013745052.1 phage tail protein -
QP018_RS03410 (QP018_03410) 701190..701642 + 453 WP_039090761.1 phage virion morphogenesis protein -
QP018_RS03415 (QP018_03415) 701631..702011 - 381 WP_013745048.1 hypothetical protein -
QP018_RS03420 (QP018_03420) 702017..702298 - 282 WP_013745047.1 hypothetical protein -
QP018_RS03425 (QP018_03425) 702377..705436 + 3060 WP_285091015.1 phage tail tape measure protein -
QP018_RS03430 (QP018_03430) 705510..705854 + 345 WP_285091016.1 hypothetical protein Toxin
QP018_RS03435 (QP018_03435) 705857..706153 + 297 WP_039094358.1 NadS family protein Antitoxin
QP018_RS03440 (QP018_03440) 706275..706901 + 627 WP_285091019.1 phage baseplate assembly protein V -
QP018_RS03445 (QP018_03445) 706903..707235 + 333 WP_285091021.1 GPW/gp25 family protein -
QP018_RS03450 (QP018_03450) 707236..708147 + 912 WP_285091022.1 baseplate J/gp47 family protein -
QP018_RS03455 (QP018_03455) 708140..708679 + 540 WP_285091024.1 phage tail protein I -
QP018_RS03460 (QP018_03460) 708698..710548 + 1851 WP_285091026.1 phage tail protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 689614..724873 35259


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(39-82)


Sequences

Toxin        


Download         Length: 115 a.a.        Molecular weight: 13109.07 Da        Isoelectric Point: 7.9955

>T283431 WP_285091016.1 NZ_CP126975:705510-705854 [Gallibacterium anatis]
MNTDKFITFIETPIFEEDRKALLSDEEYQAFQAYMLDNFHLGDFIQHTGGCQKIRWKLSGNNKGKSGGVRIIYYSLTAKG
KLYLLMMYPKSEKDNMNATEKAILKSIVDQLKGD

Download         Length: 345 bp

Antitoxin


Download         Length: 99 a.a.        Molecular weight: 11062.90 Da        Isoelectric Point: 10.3121

>AT283431 WP_039094358.1 NZ_CP126975:705857-706153 [Gallibacterium anatis]
MDKKLFDRLVKSAEQMVAIEKGEMQSAPHTVTTFRIPDVKKIRANTHLKQNEFADLLGVSTALVQSWETARRVPNGPALK
LLNIIEQQPQIIDTLRAI

Download         Length: 297 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References