Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | I | Classification (family/domain) | hok-sok/- |
Location | 140319..140588 | Replicon | plasmid pEND_Eco 12049-1 |
Accession | NZ_CP126953 | ||
Organism | Escherichia coli O78:H4 strain APEC E12049 |
Toxin (Protein)
Gene name | hok | Uniprot ID | - |
Locus tag | QQA22_RS25860 | Protein ID | WP_001372321.1 |
Coordinates | 140463..140588 (+) | Length | 42 a.a. |
Antitoxin (RNA)
Gene name | sok | ||
Locus tag | - | ||
Coordinates | 140319..140384 (-) |
Genomic Context
Location: 135361..135639 (279 bp)
Type: Others
Protein ID: WP_072127934.1
Type: Others
Protein ID: WP_072127934.1
Location: 136112..136639 (528 bp)
Type: Others
Protein ID: WP_000290793.1
Type: Others
Protein ID: WP_000290793.1
Location: 136695..136928 (234 bp)
Type: Others
Protein ID: WP_000006004.1
Type: Others
Protein ID: WP_000006004.1
Location: 136987..138945 (1959 bp)
Type: Others
Protein ID: WP_001145469.1
Type: Others
Protein ID: WP_001145469.1
Location: 139000..139434 (435 bp)
Type: Others
Protein ID: WP_000845895.1
Type: Others
Protein ID: WP_000845895.1
Location: 139431..140193 (763 bp)
Type: Others
Protein ID: Protein_137
Type: Others
Protein ID: Protein_137
Location: 140162..140386 (225 bp)
Type: Others
Protein ID: NuclAT_0
Type: Others
Protein ID: NuclAT_0
Location: 140162..140386 (225 bp)
Type: Others
Protein ID: NuclAT_0
Type: Others
Protein ID: NuclAT_0
Location: 140162..140386 (225 bp)
Type: Others
Protein ID: NuclAT_0
Type: Others
Protein ID: NuclAT_0
Location: 140162..140386 (225 bp)
Type: Others
Protein ID: NuclAT_0
Type: Others
Protein ID: NuclAT_0
Location: 140372..140521 (150 bp)
Type: Others
Protein ID: Protein_139
Type: Others
Protein ID: Protein_139
Location: 140463..140588 (126 bp)
Type: Toxin
Protein ID: WP_001372321.1
Type: Toxin
Protein ID: WP_001372321.1
Location: 140808..141038 (231 bp)
Type: Others
Protein ID: WP_001426396.1
Type: Others
Protein ID: WP_001426396.1
Location: 141279..141485 (207 bp)
Type: Others
Protein ID: WP_000547939.1
Type: Others
Protein ID: WP_000547939.1
Location: 141510..141797 (288 bp)
Type: Others
Protein ID: WP_000107535.1
Type: Others
Protein ID: WP_000107535.1
Location: 141918..142739 (822 bp)
Type: Others
Protein ID: WP_001234469.1
Type: Others
Protein ID: WP_001234469.1
Location: 143959..144342 (384 bp)
Type: Others
Protein ID: WP_001151524.1
Type: Others
Protein ID: WP_001151524.1
Location: 144529..145218 (690 bp)
Type: Others
Protein ID: WP_000283385.1
Type: Others
Protein ID: WP_000283385.1
Location: 140162..140350 (189 bp)
Type: Others
Protein ID: WP_001299721.1
Type: Others
Protein ID: WP_001299721.1
Location: 140319..140384 (66 bp)
Type: Antitoxin
Protein ID: -
Type: Antitoxin
Protein ID: -
Location: 141036..141209 (174 bp)
Type: Others
Protein ID: Protein_142
Type: Others
Protein ID: Protein_142
Location: 143036..143638 (603 bp)
Type: Others
Protein ID: WP_000243709.1
Type: Others
Protein ID: WP_000243709.1
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Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
QQA22_RS25820 | 135361..135639 | + | 279 | WP_072127934.1 | hypothetical protein | - |
QQA22_RS25825 | 136112..136639 | + | 528 | WP_000290793.1 | single-stranded DNA-binding protein | - |
QQA22_RS25830 | 136695..136928 | + | 234 | WP_000006004.1 | DUF905 domain-containing protein | - |
QQA22_RS25835 | 136987..138945 | + | 1959 | WP_001145469.1 | ParB/RepB/Spo0J family partition protein | - |
QQA22_RS25840 | 139000..139434 | + | 435 | WP_000845895.1 | conjugation system SOS inhibitor PsiB | - |
QQA22_RS25845 | 139431..140193 | + | 763 | Protein_137 | plasmid SOS inhibition protein A | - |
QQA22_RS25850 | 140162..140350 | - | 189 | WP_001299721.1 | hypothetical protein | - |
- | 140162..140386 | + | 225 | NuclAT_0 | - | - |
- | 140162..140386 | + | 225 | NuclAT_0 | - | - |
- | 140162..140386 | + | 225 | NuclAT_0 | - | - |
- | 140162..140386 | + | 225 | NuclAT_0 | - | - |
- | 140319..140384 | - | 66 | - | - | Antitoxin |
QQA22_RS25855 | 140372..140521 | + | 150 | Protein_139 | plasmid maintenance protein Mok | - |
QQA22_RS25860 | 140463..140588 | + | 126 | WP_001372321.1 | type I toxin-antitoxin system Hok family toxin | Toxin |
QQA22_RS25865 | 140808..141038 | + | 231 | WP_001426396.1 | hypothetical protein | - |
QQA22_RS25870 | 141036..141209 | - | 174 | Protein_142 | hypothetical protein | - |
QQA22_RS25875 | 141279..141485 | + | 207 | WP_000547939.1 | hypothetical protein | - |
QQA22_RS25880 | 141510..141797 | + | 288 | WP_000107535.1 | hypothetical protein | - |
QQA22_RS25885 | 141918..142739 | + | 822 | WP_001234469.1 | DUF932 domain-containing protein | - |
QQA22_RS25890 | 143036..143638 | - | 603 | WP_000243709.1 | transglycosylase SLT domain-containing protein | - |
QQA22_RS25895 | 143959..144342 | + | 384 | WP_001151524.1 | conjugal transfer relaxosome DNA-binding protein TraM | - |
QQA22_RS25900 | 144529..145218 | + | 690 | WP_000283385.1 | conjugal transfer transcriptional regulator TraJ | - |
Associated MGEs
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MGE detail | Similar MGEs | Relative position | MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Conjugative plasmid | sitABCD | vat / iroB / iroC / iroD / iroE / iroN / iucA / iucB / iucC / iucD / iutA | 1..155857 | 155857 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 42 a.a. Molecular weight: 4780.69 Da Isoelectric Point: 8.5110
>T283367 WP_001372321.1 NZ_CP126953:140463-140588 [Escherichia coli O78:H4]
VLIVCLTLLIFTYLTRKSLCEIRYRDGHREVAAFMAYESGK
VLIVCLTLLIFTYLTRKSLCEIRYRDGHREVAAFMAYESGK
Download Length: 126 bp
Antitoxin
Download Length: 66 bp
>AT283367 NZ_CP126953:c140384-140319 [Escherichia coli O78:H4]
GTGGACTAGACATAGGGATGCCTCGTGGTGGTTAATGAAAATTAACTTACTACGGGGCTATCTTCT
GTGGACTAGACATAGGGATGCCTCGTGGTGGTTAATGAAAATTAACTTACTACGGGGCTATCTTCT
Structures
Toxin
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Source | ID | Structure |
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No matching records found |