Detailed information of TA system TA283338

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): ldrD-rdlD/Ldr(toxin)
• Location: 426107..426329
• Replicon: chromosome
• Accession: NZ_CP126952
• Organism: Escherichia coli O78:H4 strain APEC E12049

Toxin (Protein)

• Gene name: ldrD
• Uniprot ID: A0A829L523
• Locus tag: QQA22_RS02000
• Protein ID: WP_000170738.1
• Coordinates: 426107..426214 (-)
• Length: 36 a.a.

Antitoxin (RNA)

Gene name	rdlD
Locus tag	-
Coordinates	426263..426329 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
QQA22_RS01970	421136..422707	+	1572	WP_001204944.1	cellulose biosynthesis c-di-GMP-binding protein BcsE	-
QQA22_RS01975	422704..422895	+	192	WP_000988308.1	cellulose biosynthesis protein BcsF	-
QQA22_RS01980	422892..424571	+	1680	WP_289245627.1	cellulose biosynthesis protein BcsG	-
QQA22_RS01985	424658..424765	-	108	WP_001295224.1	type I toxin-antitoxin system toxin Ldr family protein	-
QQA22_RS01990	425141..425248	-	108	WP_001295224.1	type I toxin-antitoxin system toxin Ldr family protein	-
QQA22_RS01995	425624..425731	-	108	WP_001295224.1	type I toxin-antitoxin system toxin Ldr family protein	-
QQA22_RS02000	426107..426214	-	108	WP_000170738.1	type I toxin-antitoxin system toxin Ldr family protein	Toxin
-	426263..426329	+	67	-	-	Antitoxin
QQA22_RS02005	426690..427961	+	1272	WP_001318103.1	aromatic amino acid transport family protein	-
QQA22_RS02010	427991..428995	-	1005	WP_000107036.1	dipeptide ABC transporter ATP-binding subunit DppF	-
QQA22_RS02015	428992..429975	-	984	WP_001196486.1	dipeptide ABC transporter ATP-binding protein	-
QQA22_RS02020	429986..430888	-	903	WP_000084677.1	dipeptide ABC transporter permease DppC	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Type I toxin-antitoxin system, toxin Ldr (1-35)

Sequences

Toxin

Protein

• Length: 36 a.a.
• Molecular weight: 3864.67 Da
• Isoelectric Point: 9.0157

>T283338 WP_000170738.1 NZ_CP126952:c426214-426107 [Escherichia coli O78:H4]
MTLAELGMAFWHDLAAPVIAGILASLIVNWLNKRK

Nucleotide

• Length: 108 bp

Antitoxin

Nucleotide

• Length: 67 bp

>AT283338 NZ_CP126952:426263-426329 [Escherichia coli O78:H4]
GTCTAGGTTCAAGATTAGCCCCCGTGATGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTTCTC

Structures

Toxin

• AlphaFold DB: A0A829L523

Antitoxin