Detailed information of TA system TA283303

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): ldrD-rdlD/Ldr(toxin)
• Location: 186006..186228
• Replicon: chromosome
• Accession: NZ_CP126948
• Organism: Escherichia coli O78:H4 strain APEC E14033

Toxin (Protein)

• Gene name: ldrD
• Uniprot ID: S1NWX0
• Locus tag: QQA23_RS00885
• Protein ID: WP_001295224.1
• Coordinates: 186121..186228 (+)
• Length: 36 a.a.

Antitoxin (RNA)

Gene name	rdlD
Locus tag	-
Coordinates	186006..186072 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
QQA23_RS00860	181394..182377	+	984	WP_001196486.1	dipeptide ABC transporter ATP-binding protein	-
QQA23_RS00865	182374..183378	+	1005	WP_000107036.1	dipeptide ABC transporter ATP-binding subunit DppF	-
QQA23_RS00870	183408..184679	-	1272	WP_001318103.1	aromatic amino acid transport family protein	-
QQA23_RS00875	185155..185262	+	108	WP_000170738.1	type I toxin-antitoxin system toxin Ldr family protein	-
QQA23_RS00880	185638..185745	+	108	WP_001295224.1	type I toxin-antitoxin system toxin Ldr family protein	-
-	186006..186072	-	67	-	-	Antitoxin
QQA23_RS00885	186121..186228	+	108	WP_001295224.1	type I toxin-antitoxin system toxin Ldr family protein	Toxin
QQA23_RS00890	186604..186711	+	108	WP_001295224.1	type I toxin-antitoxin system toxin Ldr family protein	-
QQA23_RS00895	186798..188477	-	1680	WP_001562264.1	cellulose biosynthesis protein BcsG	-
QQA23_RS00900	188474..188665	-	192	WP_000988308.1	cellulose biosynthesis protein BcsF	-
QQA23_RS00905	188662..190233	-	1572	WP_001204944.1	cellulose biosynthesis c-di-GMP-binding protein BcsE	-
QQA23_RS00910	190506..190694	+	189	WP_001063315.1	cellulose biosynthesis protein BcsR	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Type I toxin-antitoxin system, toxin Ldr (1-35)

Sequences

Toxin

Protein

• Length: 36 a.a.
• Molecular weight: 3882.70 Da
• Isoelectric Point: 9.0157

>T283303 WP_001295224.1 NZ_CP126948:186121-186228 [Escherichia coli O78:H4]
MTLAELGMAFWHDLAAPVIAGILASMIVNWLNKRK

Nucleotide

• Length: 108 bp

Antitoxin

Nucleotide

• Length: 67 bp

>AT283303 NZ_CP126948:c186072-186006 [Escherichia coli O78:H4]
GTCTAGATGCAAGAATGGCCCCCGTGGTGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTTCTC

Structures

Toxin

• AlphaFold DB: A0A4P7TSJ7

Antitoxin