Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) ldrD-ohsC/Ldr(toxin)
Location 1835243..1835464 Replicon chromosome
Accession NZ_CP126946
Organism Escherichia coli O78:H51 strain APEC E18005

Toxin (Protein)


Gene name ldrD Uniprot ID E0IV43
Locus tag QQA24_RS08945 Protein ID WP_000170926.1
Coordinates 1835243..1835350 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name ohsC
Locus tag -
Coordinates 1835403..1835464 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QQA24_RS08915 (1830552) 1830552..1831634 + 1083 WP_000804726.1 peptide chain release factor 1 -
QQA24_RS08920 (1831634) 1831634..1832467 + 834 WP_000456571.1 peptide chain release factor N(5)-glutamine methyltransferase -
QQA24_RS08925 (1832464) 1832464..1832856 + 393 WP_000200378.1 invasion regulator SirB2 -
QQA24_RS08930 (1832860) 1832860..1833669 + 810 WP_001257044.1 invasion regulator SirB1 -
QQA24_RS08935 (1833705) 1833705..1834559 + 855 WP_000811065.1 3-deoxy-8-phosphooctulonate synthase -
QQA24_RS08940 (1834708) 1834708..1834815 - 108 WP_000170954.1 type I toxin-antitoxin system toxin Ldr family protein -
- (1834865) 1834865..1834928 + 64 NuclAT_15 - -
- (1834865) 1834865..1834928 + 64 NuclAT_15 - -
- (1834865) 1834865..1834928 + 64 NuclAT_15 - -
- (1834865) 1834865..1834928 + 64 NuclAT_15 - -
- (1834865) 1834865..1834928 + 64 NuclAT_18 - -
- (1834865) 1834865..1834928 + 64 NuclAT_18 - -
- (1834865) 1834865..1834928 + 64 NuclAT_18 - -
- (1834865) 1834865..1834928 + 64 NuclAT_18 - -
- (1834865) 1834865..1834928 + 64 NuclAT_21 - -
- (1834865) 1834865..1834928 + 64 NuclAT_21 - -
- (1834865) 1834865..1834928 + 64 NuclAT_21 - -
- (1834865) 1834865..1834928 + 64 NuclAT_21 - -
- (1834865) 1834865..1834928 + 64 NuclAT_24 - -
- (1834865) 1834865..1834928 + 64 NuclAT_24 - -
- (1834865) 1834865..1834928 + 64 NuclAT_24 - -
- (1834865) 1834865..1834928 + 64 NuclAT_24 - -
- (1834865) 1834865..1834928 + 64 NuclAT_27 - -
- (1834865) 1834865..1834928 + 64 NuclAT_27 - -
- (1834865) 1834865..1834928 + 64 NuclAT_27 - -
- (1834865) 1834865..1834928 + 64 NuclAT_27 - -
- (1834865) 1834865..1834928 + 64 NuclAT_30 - -
- (1834865) 1834865..1834928 + 64 NuclAT_30 - -
- (1834865) 1834865..1834928 + 64 NuclAT_30 - -
- (1834865) 1834865..1834928 + 64 NuclAT_30 - -
- (1834863) 1834863..1834929 + 67 NuclAT_43 - -
- (1834863) 1834863..1834929 + 67 NuclAT_43 - -
- (1834863) 1834863..1834929 + 67 NuclAT_43 - -
- (1834863) 1834863..1834929 + 67 NuclAT_43 - -
- (1834863) 1834863..1834929 + 67 NuclAT_46 - -
- (1834863) 1834863..1834929 + 67 NuclAT_46 - -
- (1834863) 1834863..1834929 + 67 NuclAT_46 - -
- (1834863) 1834863..1834929 + 67 NuclAT_46 - -
- (1834863) 1834863..1834929 + 67 NuclAT_49 - -
- (1834863) 1834863..1834929 + 67 NuclAT_49 - -
- (1834863) 1834863..1834929 + 67 NuclAT_49 - -
- (1834863) 1834863..1834929 + 67 NuclAT_49 - -
QQA24_RS08945 (1835243) 1835243..1835350 - 108 WP_000170926.1 type I toxin-antitoxin system toxin Ldr family protein Toxin
- (1835403) 1835403..1835464 + 62 NuclAT_14 - Antitoxin
- (1835403) 1835403..1835464 + 62 NuclAT_14 - Antitoxin
- (1835403) 1835403..1835464 + 62 NuclAT_14 - Antitoxin
- (1835403) 1835403..1835464 + 62 NuclAT_14 - Antitoxin
- (1835403) 1835403..1835464 + 62 NuclAT_17 - Antitoxin
- (1835403) 1835403..1835464 + 62 NuclAT_17 - Antitoxin
- (1835403) 1835403..1835464 + 62 NuclAT_17 - Antitoxin
- (1835403) 1835403..1835464 + 62 NuclAT_17 - Antitoxin
- (1835403) 1835403..1835464 + 62 NuclAT_20 - Antitoxin
- (1835403) 1835403..1835464 + 62 NuclAT_20 - Antitoxin
- (1835403) 1835403..1835464 + 62 NuclAT_20 - Antitoxin
- (1835403) 1835403..1835464 + 62 NuclAT_20 - Antitoxin
- (1835403) 1835403..1835464 + 62 NuclAT_23 - Antitoxin
- (1835403) 1835403..1835464 + 62 NuclAT_23 - Antitoxin
- (1835403) 1835403..1835464 + 62 NuclAT_23 - Antitoxin
- (1835403) 1835403..1835464 + 62 NuclAT_23 - Antitoxin
- (1835403) 1835403..1835464 + 62 NuclAT_26 - Antitoxin
- (1835403) 1835403..1835464 + 62 NuclAT_26 - Antitoxin
- (1835403) 1835403..1835464 + 62 NuclAT_26 - Antitoxin
- (1835403) 1835403..1835464 + 62 NuclAT_26 - Antitoxin
- (1835403) 1835403..1835464 + 62 NuclAT_29 - Antitoxin
- (1835403) 1835403..1835464 + 62 NuclAT_29 - Antitoxin
- (1835403) 1835403..1835464 + 62 NuclAT_29 - Antitoxin
- (1835403) 1835403..1835464 + 62 NuclAT_29 - Antitoxin
- (1835403) 1835403..1835465 + 63 NuclAT_44 - -
- (1835403) 1835403..1835465 + 63 NuclAT_44 - -
- (1835403) 1835403..1835465 + 63 NuclAT_44 - -
- (1835403) 1835403..1835465 + 63 NuclAT_44 - -
- (1835403) 1835403..1835465 + 63 NuclAT_47 - -
- (1835403) 1835403..1835465 + 63 NuclAT_47 - -
- (1835403) 1835403..1835465 + 63 NuclAT_47 - -
- (1835403) 1835403..1835465 + 63 NuclAT_47 - -
- (1835403) 1835403..1835465 + 63 NuclAT_50 - -
- (1835403) 1835403..1835465 + 63 NuclAT_50 - -
- (1835403) 1835403..1835465 + 63 NuclAT_50 - -
- (1835403) 1835403..1835465 + 63 NuclAT_50 - -
- (1835403) 1835403..1835466 + 64 NuclAT_32 - -
- (1835403) 1835403..1835466 + 64 NuclAT_32 - -
- (1835403) 1835403..1835466 + 64 NuclAT_32 - -
- (1835403) 1835403..1835466 + 64 NuclAT_32 - -
- (1835403) 1835403..1835466 + 64 NuclAT_34 - -
- (1835403) 1835403..1835466 + 64 NuclAT_34 - -
- (1835403) 1835403..1835466 + 64 NuclAT_34 - -
- (1835403) 1835403..1835466 + 64 NuclAT_34 - -
- (1835403) 1835403..1835466 + 64 NuclAT_36 - -
- (1835403) 1835403..1835466 + 64 NuclAT_36 - -
- (1835403) 1835403..1835466 + 64 NuclAT_36 - -
- (1835403) 1835403..1835466 + 64 NuclAT_36 - -
- (1835403) 1835403..1835466 + 64 NuclAT_38 - -
- (1835403) 1835403..1835466 + 64 NuclAT_38 - -
- (1835403) 1835403..1835466 + 64 NuclAT_38 - -
- (1835403) 1835403..1835466 + 64 NuclAT_38 - -
- (1835403) 1835403..1835466 + 64 NuclAT_40 - -
- (1835403) 1835403..1835466 + 64 NuclAT_40 - -
- (1835403) 1835403..1835466 + 64 NuclAT_40 - -
- (1835403) 1835403..1835466 + 64 NuclAT_40 - -
- (1835403) 1835403..1835466 + 64 NuclAT_42 - -
- (1835403) 1835403..1835466 + 64 NuclAT_42 - -
- (1835403) 1835403..1835466 + 64 NuclAT_42 - -
- (1835403) 1835403..1835466 + 64 NuclAT_42 - -
QQA24_RS08950 (1835779) 1835779..1835886 - 108 WP_074147554.1 type I toxin-antitoxin system toxin Ldr family protein -
- (1835934) 1835934..1835999 + 66 NuclAT_13 - -
- (1835934) 1835934..1835999 + 66 NuclAT_13 - -
- (1835934) 1835934..1835999 + 66 NuclAT_13 - -
- (1835934) 1835934..1835999 + 66 NuclAT_13 - -
- (1835934) 1835934..1835999 + 66 NuclAT_16 - -
- (1835934) 1835934..1835999 + 66 NuclAT_16 - -
- (1835934) 1835934..1835999 + 66 NuclAT_16 - -
- (1835934) 1835934..1835999 + 66 NuclAT_16 - -
- (1835934) 1835934..1835999 + 66 NuclAT_19 - -
- (1835934) 1835934..1835999 + 66 NuclAT_19 - -
- (1835934) 1835934..1835999 + 66 NuclAT_19 - -
- (1835934) 1835934..1835999 + 66 NuclAT_19 - -
- (1835934) 1835934..1835999 + 66 NuclAT_22 - -
- (1835934) 1835934..1835999 + 66 NuclAT_22 - -
- (1835934) 1835934..1835999 + 66 NuclAT_22 - -
- (1835934) 1835934..1835999 + 66 NuclAT_22 - -
- (1835934) 1835934..1835999 + 66 NuclAT_25 - -
- (1835934) 1835934..1835999 + 66 NuclAT_25 - -
- (1835934) 1835934..1835999 + 66 NuclAT_25 - -
- (1835934) 1835934..1835999 + 66 NuclAT_25 - -
- (1835934) 1835934..1835999 + 66 NuclAT_28 - -
- (1835934) 1835934..1835999 + 66 NuclAT_28 - -
- (1835934) 1835934..1835999 + 66 NuclAT_28 - -
- (1835934) 1835934..1835999 + 66 NuclAT_28 - -
- (1835935) 1835935..1836000 + 66 NuclAT_45 - -
- (1835935) 1835935..1836000 + 66 NuclAT_45 - -
- (1835935) 1835935..1836000 + 66 NuclAT_45 - -
- (1835935) 1835935..1836000 + 66 NuclAT_45 - -
- (1835935) 1835935..1836000 + 66 NuclAT_48 - -
- (1835935) 1835935..1836000 + 66 NuclAT_48 - -
- (1835935) 1835935..1836000 + 66 NuclAT_48 - -
- (1835935) 1835935..1836000 + 66 NuclAT_48 - -
- (1835935) 1835935..1836000 + 66 NuclAT_51 - -
- (1835935) 1835935..1836000 + 66 NuclAT_51 - -
- (1835935) 1835935..1836000 + 66 NuclAT_51 - -
- (1835935) 1835935..1836000 + 66 NuclAT_51 - -
- (1835934) 1835934..1836001 + 68 NuclAT_31 - -
- (1835934) 1835934..1836001 + 68 NuclAT_31 - -
- (1835934) 1835934..1836001 + 68 NuclAT_31 - -
- (1835934) 1835934..1836001 + 68 NuclAT_31 - -
- (1835934) 1835934..1836001 + 68 NuclAT_33 - -
- (1835934) 1835934..1836001 + 68 NuclAT_33 - -
- (1835934) 1835934..1836001 + 68 NuclAT_33 - -
- (1835934) 1835934..1836001 + 68 NuclAT_33 - -
- (1835934) 1835934..1836001 + 68 NuclAT_35 - -
- (1835934) 1835934..1836001 + 68 NuclAT_35 - -
- (1835934) 1835934..1836001 + 68 NuclAT_35 - -
- (1835934) 1835934..1836001 + 68 NuclAT_35 - -
- (1835934) 1835934..1836001 + 68 NuclAT_37 - -
- (1835934) 1835934..1836001 + 68 NuclAT_37 - -
- (1835934) 1835934..1836001 + 68 NuclAT_37 - -
- (1835934) 1835934..1836001 + 68 NuclAT_37 - -
- (1835934) 1835934..1836001 + 68 NuclAT_39 - -
- (1835934) 1835934..1836001 + 68 NuclAT_39 - -
- (1835934) 1835934..1836001 + 68 NuclAT_39 - -
- (1835934) 1835934..1836001 + 68 NuclAT_39 - -
- (1835934) 1835934..1836001 + 68 NuclAT_41 - -
- (1835934) 1835934..1836001 + 68 NuclAT_41 - -
- (1835934) 1835934..1836001 + 68 NuclAT_41 - -
- (1835934) 1835934..1836001 + 68 NuclAT_41 - -
QQA24_RS08955 (1836291) 1836291..1837391 - 1101 WP_001295620.1 sodium-potassium/proton antiporter ChaA -
QQA24_RS08960 (1837661) 1837661..1837891 + 231 WP_001146442.1 putative cation transport regulator ChaB -
QQA24_RS08965 (1838048) 1838048..1838743 + 696 WP_001297117.1 glutathione-specific gamma-glutamylcyclotransferase -
QQA24_RS08970 (1838787) 1838787..1839140 - 354 WP_001169669.1 DsrE/F sulfur relay family protein YchN -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Type I toxin-antitoxin system, toxin Ldr

(1-35)


Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 3983.84 Da        Isoelectric Point: 11.6501

>T283271 WP_000170926.1 NZ_CP126946:c1835350-1835243 [Escherichia coli O78:H51]
MTLAKFAMIFWHDLAAPILAGIITAAIVGWWRNRK

Download         Length: 108 bp

Antitoxin


Download         Length: 62 bp

>AT283271 NZ_CP126946:1835403-1835464 [Escherichia coli O78:H51]
TGGTTCAAGATTAGCCCCCGTTCTGTTGTCAGGTTTTACCTCTCAACGTGCGGGGGTTTTCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0E0Y1K9

Antitoxin

Download structure file

References