Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) symE-ohsC/SymE(toxin)
Location 4300275..4300687 Replicon chromosome
Accession NZ_CP126942
Organism Escherichia coli O1:K1:H7 strain APEC E18006

Toxin (Protein)


Gene name symE Uniprot ID -
Locus tag QQA29_RS21295 Protein ID WP_001622590.1
Coordinates 4300346..4300687 (+) Length 114 a.a.

Antitoxin (RNA)


Gene name ohsC
Locus tag -
Coordinates 4300275..4300351 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QQA29_RS21285 (4297138) 4297138..4298727 + 1590 WP_001063204.1 type I restriction-modification system methyltransferase -
QQA29_RS21290 (4298724) 4298724..4300118 + 1395 WP_001272447.1 type I restriction-modification system specificity subunit -
- (4300275) 4300275..4300351 - 77 NuclAT_5 - Antitoxin
- (4300275) 4300275..4300351 - 77 NuclAT_5 - Antitoxin
- (4300275) 4300275..4300351 - 77 NuclAT_5 - Antitoxin
- (4300275) 4300275..4300351 - 77 NuclAT_5 - Antitoxin
- (4300275) 4300275..4300351 - 77 NuclAT_6 - Antitoxin
- (4300275) 4300275..4300351 - 77 NuclAT_6 - Antitoxin
- (4300275) 4300275..4300351 - 77 NuclAT_6 - Antitoxin
- (4300275) 4300275..4300351 - 77 NuclAT_6 - Antitoxin
QQA29_RS21295 (4300346) 4300346..4300687 + 342 WP_001622590.1 endoribonuclease SymE Toxin
QQA29_RS21300 (4300849) 4300849..4302228 + 1380 WP_032147538.1 5-methylcytosine-specific restriction endonuclease subunit McrB -
QQA29_RS21305 (4302228) 4302228..4303274 + 1047 WP_000437621.1 5-methylcytosine-specific restriction endonuclease system specificity protein McrC -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin SymE-like

(20-71)


Sequences

Toxin        


Download         Length: 114 a.a.        Molecular weight: 12144.98 Da        Isoelectric Point: 9.1114

>T283214 WP_001622590.1 NZ_CP126942:4300346-4300687 [Escherichia coli O1:K1:H7]
MTDTHSIAQPFEAEVSPANNRHVTVGYASRYPGYSRIPAITLKGQWLEAAGFATGTAVDVKVMEGCIVLTAQPPAAEESE
LMQSLRQVCKLSARKQKQVQAFIGVIAGKQKVA

Download         Length: 342 bp

Antitoxin


Download         Length: 77 bp

>AT283214 NZ_CP126942:c4300351-4300275 [Escherichia coli O1:K1:H7]
AGTCATAACTGCTATTCTCCAGGAATAGTGATTGTGATTAGCGATGCAGGTGTGTTGGCGCACATCCGCACCGCGCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References