Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) hok-sok/-
Location 4174457..4174715 Replicon chromosome
Accession NZ_CP126942
Organism Escherichia coli O1:K1:H7 strain APEC E18006

Toxin (Protein)


Gene name hokC Uniprot ID S1NX00
Locus tag QQA29_RS20630 Protein ID WP_000809168.1
Coordinates 4174563..4174715 (+) Length 51 a.a.

Antitoxin (RNA)


Gene name sokC
Locus tag -
Coordinates 4174457..4174514 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QQA29_RS20615 4170289..4171548 - 1260 WP_000494924.1 hypothetical protein -
QQA29_RS20620 4171677..4173170 - 1494 WP_001350775.1 sulfatase-like hydrolase/transferase -
QQA29_RS20625 4173190..4173951 - 762 WP_001274823.1 outer membrane protein OmpK -
- 4174457..4174514 - 58 - - Antitoxin
QQA29_RS20630 4174563..4174715 + 153 WP_000809168.1 type I toxin-antitoxin system toxin MokC Toxin
QQA29_RS20635 4174820..4175950 - 1131 WP_001118464.1 molecular chaperone DnaJ -
QQA29_RS20640 4176039..4177955 - 1917 WP_000516135.1 molecular chaperone DnaK -
QQA29_RS20645 4178327..4178731 + 405 WP_000843687.1 DUF2541 family protein -
QQA29_RS20650 4178757..4179470 + 714 WP_001102393.1 acidic protein MsyB -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Hok/gef cell toxic protein

(6-47)


Sequences

Toxin        


Download         Length: 51 a.a.        Molecular weight: 5501.57 Da        Isoelectric Point: 7.1312

>T283213 WP_000809168.1 NZ_CP126942:4174563-4174715 [Escherichia coli O1:K1:H7]
MKQHKAMIVALIVICITAVVAALVTRKDLCEVHIRTGQTEVAVFTAYESE

Download         Length: 153 bp

Antitoxin


Download         Length: 58 bp

>AT283213 NZ_CP126942:c4174514-4174457 [Escherichia coli O1:K1:H7]
GTTCTGCATATAGGGGGCCTCGGGTTGATGGTAAAATATCACTCGGGGCTTTTCTCTA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB S1NX00

Antitoxin

Download structure file

References