Detailed information of TA system TA283197

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): ldrD-rdlD/Ldr(toxin)
• Location: 188333..188555
• Replicon: chromosome
• Accession: NZ_CP126942
• Organism: Escherichia coli O1:K1:H7 strain APEC E18006

Toxin (Protein)

• Gene name: ldrD
• Uniprot ID: S1NWX0
• Locus tag: QQA29_RS00895
• Protein ID: WP_001295224.1
• Coordinates: 188448..188555 (+)
• Length: 36 a.a.

Antitoxin (RNA)

Gene name	rdlD
Locus tag	-
Coordinates	188333..188399 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
QQA29_RS00875	184205..185188	+	984	WP_001196477.1	dipeptide ABC transporter ATP-binding protein	-
QQA29_RS00880	185185..186189	+	1005	WP_000103579.1	dipeptide ABC transporter ATP-binding subunit DppF	-
QQA29_RS00885	186219..187490	-	1272	WP_001332306.1	aromatic amino acid transport family protein	-
QQA29_RS00890	187966..188073	+	108	WP_000170745.1	type I toxin-antitoxin system toxin Ldr family protein	-
-	188333..188399	-	67	-	-	Antitoxin
QQA29_RS00895	188448..188555	+	108	WP_001295224.1	type I toxin-antitoxin system toxin Ldr family protein	Toxin
QQA29_RS00900	188931..189038	+	108	WP_001295224.1	type I toxin-antitoxin system toxin Ldr family protein	-
QQA29_RS00905	189124..190803	-	1680	WP_000191567.1	cellulose biosynthesis protein BcsG	-
QQA29_RS00910	190800..190991	-	192	WP_000988308.1	cellulose biosynthesis protein BcsF	-
QQA29_RS00915	190988..192559	-	1572	WP_001204957.1	cellulose biosynthesis c-di-GMP-binding protein BcsE	-
QQA29_RS00920	192832..193020	+	189	WP_001063314.1	cellulose biosynthesis protein BcsR	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Type I toxin-antitoxin system, toxin Ldr (1-35)

Sequences

Toxin

Protein

• Length: 36 a.a.
• Molecular weight: 3882.70 Da
• Isoelectric Point: 9.0157

>T283197 WP_001295224.1 NZ_CP126942:188448-188555 [Escherichia coli O1:K1:H7]
MTLAELGMAFWHDLAAPVIAGILASMIVNWLNKRK

Nucleotide

• Length: 108 bp

Antitoxin

Nucleotide

• Length: 67 bp

>AT283197 NZ_CP126942:c188399-188333 [Escherichia coli O1:K1:H7]
GTCTAGATGCAAGAATGGCCCCCGTGATGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTTCTC

Structures

Toxin

• AlphaFold DB: A0A4P7TSJ7

Antitoxin