Detailed information of TA system TA283045

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): ldrD-rdlD/Ldr(toxin)
• Location: 189666..189888
• Replicon: chromosome
• Accession: NZ_CP126928
• Organism: Escherichia coli O2:K1:H4 strain APEC E12053

Toxin (Protein)

• Gene name: ldrD
• Uniprot ID: S1NWX0
• Locus tag: QQA27_RS00900
• Protein ID: WP_001295224.1
• Coordinates: 189781..189888 (+)
• Length: 36 a.a.

Antitoxin (RNA)

Gene name	rdlD
Locus tag	-
Coordinates	189666..189724 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
QQA27_RS00875	185055..186038	+	984	WP_001196477.1	dipeptide ABC transporter ATP-binding protein	-
QQA27_RS00880	186035..187039	+	1005	WP_000103579.1	dipeptide ABC transporter ATP-binding subunit DppF	-
QQA27_RS00885	187069..188340	-	1272	WP_001332306.1	aromatic amino acid transport family protein	-
QQA27_RS00890	188816..188923	+	108	WP_000170745.1	type I toxin-antitoxin system toxin Ldr family protein	-
QQA27_RS00895	189298..189405	+	108	WP_001295224.1	type I toxin-antitoxin system toxin Ldr family protein	-
-	189666..189724	-	59	-	-	Antitoxin
QQA27_RS00900	189781..189888	+	108	WP_001295224.1	type I toxin-antitoxin system toxin Ldr family protein	Toxin
QQA27_RS00905	189974..191653	-	1680	WP_000191567.1	cellulose biosynthesis protein BcsG	-
QQA27_RS00910	191650..191841	-	192	WP_000988308.1	cellulose biosynthesis protein BcsF	-
QQA27_RS00915	191838..193409	-	1572	WP_001204957.1	cellulose biosynthesis c-di-GMP-binding protein BcsE	-
QQA27_RS00920	193682..193870	+	189	WP_001063314.1	cellulose biosynthesis protein BcsR	-
QQA27_RS00925	193882..194634	+	753	WP_000279545.1	cellulose biosynthesis protein BcsQ	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Type I toxin-antitoxin system, toxin Ldr (1-35)

Sequences

Toxin

Protein

• Length: 36 a.a.
• Molecular weight: 3882.70 Da
• Isoelectric Point: 9.0157

>T283045 WP_001295224.1 NZ_CP126928:189781-189888 [Escherichia coli O2:K1:H4]
MTLAELGMAFWHDLAAPVIAGILASMIVNWLNKRK

Nucleotide

• Length: 108 bp

Antitoxin

Nucleotide

• Length: 59 bp

>AT283045 NZ_CP126928:c189724-189666 [Escherichia coli O2:K1:H4]
TCAAGATTAGCCCCCGTGATGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTTCTC

Structures

Toxin

• AlphaFold DB: A0A4P7TSJ7

Antitoxin