Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-YefM
Location 48995..49497 Replicon plasmid unnamed2
Accession NZ_CP126683
Organism Pantoea agglomerans strain FL1

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag QPJ96_RS21360 Protein ID WP_161736637.1
Coordinates 49243..49497 (+) Length 85 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID A0A349IE86
Locus tag QPJ96_RS21355 Protein ID WP_010256861.1
Coordinates 48995..49246 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QPJ96_RS21340 (QPJ96_21340) 44726..46180 + 1455 WP_161736305.1 flagellin -
QPJ96_RS21345 (QPJ96_21345) 46518..47831 + 1314 WP_161736640.1 CitMHS family transporter -
QPJ96_RS21350 (QPJ96_21350) 47997..48836 + 840 WP_285088954.1 MBL fold metallo-hydrolase -
QPJ96_RS21355 (QPJ96_21355) 48995..49246 + 252 WP_010256861.1 YoeB-YefM toxin-antitoxin system antitoxin YefM Antitoxin
QPJ96_RS21360 (QPJ96_21360) 49243..49497 + 255 WP_161736637.1 Txe/YoeB family addiction module toxin Toxin
QPJ96_RS21365 (QPJ96_21365) 49571..52108 - 2538 WP_285088955.1 excinuclease ABC subunit UvrA -
QPJ96_RS21370 (QPJ96_21370) 52329..52721 - 393 WP_222925669.1 transcriptional regulator -
QPJ96_RS21375 (QPJ96_21375) 52721..52822 - 102 WP_260059782.1 type II toxin-antitoxin system HigB family toxin -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Mobilizable plasmid - - 1..161161 161161


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 9900.25 Da        Isoelectric Point: 8.8485

>T283011 WP_161736637.1 NZ_CP126683:49243-49497 [Pantoea agglomerans]
VKLTWSEETWEDYLYWQDTDKKTVKKINELLKDASRTPFEGKGKPEPLKHNLAGFWSRRITAEHRLVYAVSGDALLIASC
RYHY

Download         Length: 255 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9339.48 Da        Isoelectric Point: 4.4155

>AT283011 WP_010256861.1 NZ_CP126683:48995-49246 [Pantoea agglomerans]
MRAISYSEARQNLSATMVQTVEDKAPVLITRQNGESCVLMSLEEYNSLEETAYLLRSPKNARRLMDSIESLQSGNGTDRD
IIE

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A349IE86

References