Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/COG4683-HTH_37
Location 3716278..3716923 Replicon chromosome
Accession NZ_CP126681
Organism Pantoea agglomerans strain FL1

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag QPJ96_RS17565 Protein ID WP_285086677.1
Coordinates 3716570..3716923 (-) Length 118 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag QPJ96_RS17560 Protein ID WP_161733580.1
Coordinates 3716278..3716577 (-) Length 100 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QPJ96_RS17545 (QPJ96_17545) 3712192..3713976 - 1785 WP_253420768.1 GMC family oxidoreductase -
QPJ96_RS17550 (QPJ96_17550) 3713979..3714713 - 735 WP_161733584.1 gluconate 2-dehydrogenase subunit 3 family protein -
QPJ96_RS17555 (QPJ96_17555) 3714989..3716230 + 1242 WP_161733582.1 peptide antibiotic transporter SbmA -
QPJ96_RS17560 (QPJ96_17560) 3716278..3716577 - 300 WP_161733580.1 helix-turn-helix transcriptional regulator Antitoxin
QPJ96_RS17565 (QPJ96_17565) 3716570..3716923 - 354 WP_285086677.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
QPJ96_RS17570 (QPJ96_17570) 3717133..3718185 - 1053 WP_161733578.1 YncE family protein -
QPJ96_RS17575 (QPJ96_17575) 3718383..3718592 - 210 WP_009092571.1 DUF1471 domain-containing protein -
QPJ96_RS17580 (QPJ96_17580) 3718805..3719992 - 1188 WP_285086679.1 MFS transporter -
QPJ96_RS17585 (QPJ96_17585) 3720097..3721062 + 966 WP_161733574.1 AraC family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(12-107)

Antitoxin

Cro/C1-type helix-turn-helix domain

(31-84)


Sequences

Toxin        


Download         Length: 118 a.a.        Molecular weight: 13379.27 Da        Isoelectric Point: 6.4741

>T283007 WP_285086677.1 NZ_CP126681:c3716923-3716570 [Pantoea agglomerans]
MWDVDTTKRFDEWFKAQSEELKEDMLAAIVILSEYGPHLAKPFADTVDGSDFPNMKELRVQHQGKPIRAFFAFDPSRRGI
VLCAGDKTGVKEKKFYKDMIKLADAEFRKYLNGGDNG

Download         Length: 354 bp

Antitoxin


Download         Length: 100 a.a.        Molecular weight: 11094.92 Da        Isoelectric Point: 9.8101

>AT283007 WP_161733580.1 NZ_CP126681:c3716577-3716278 [Pantoea agglomerans]
MANLKELMANQSPESRERIAKKVDAMRQAIALHMLREELNLSQTEMAQAMGVKQPTIARMEQADNDPRLSTLKRYVTALG
GEISIDVKLPTGKRIAFDL

Download         Length: 300 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References