Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/COG4683-HTH_37
Location 1597519..1598179 Replicon chromosome
Accession NZ_CP126681
Organism Pantoea agglomerans strain FL1

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag QPJ96_RS07495 Protein ID WP_253419151.1
Coordinates 1597519..1597872 (+) Length 118 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag QPJ96_RS07500 Protein ID WP_033733169.1
Coordinates 1597877..1598179 (+) Length 101 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QPJ96_RS07480 (QPJ96_07480) 1593122..1593403 + 282 WP_285088349.1 hypothetical protein -
QPJ96_RS07485 (QPJ96_07485) 1593557..1595719 - 2163 WP_285088350.1 ferric-rhodotorulic acid/ferric-coprogen receptor FhuE -
QPJ96_RS07490 (QPJ96_07490) 1596145..1597233 + 1089 WP_161736888.1 YncE family protein -
QPJ96_RS07495 (QPJ96_07495) 1597519..1597872 + 354 WP_253419151.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
QPJ96_RS07500 (QPJ96_07500) 1597877..1598179 + 303 WP_033733169.1 XRE family transcriptional regulator Antitoxin
QPJ96_RS07510 (QPJ96_07510) 1598849..1599772 + 924 WP_285088351.1 sugar ABC transporter substrate-binding protein -
QPJ96_RS07515 (QPJ96_07515) 1599805..1601289 + 1485 WP_098052921.1 sugar ABC transporter ATP-binding protein -
QPJ96_RS07520 (QPJ96_07520) 1601313..1602338 + 1026 WP_190285965.1 ABC transporter permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(13-106)

Antitoxin

Cro/C1-type helix-turn-helix domain

(33-79)


Sequences

Toxin        


Download         Length: 118 a.a.        Molecular weight: 13628.75 Da        Isoelectric Point: 10.1378

>T283004 WP_253419151.1 NZ_CP126681:1597519-1597872 [Pantoea agglomerans]
VWMIKTTERFDRWFTLLNDSDRACVLAALMVLREKGPGLSRPYADTIKGSAYINMKELRIQSRGDPIRAFFAFDPNRTAI
VLCAGNKAGNEKRFYREMLPVADREFTHWLKSFNHKE

Download         Length: 354 bp

Antitoxin


Download         Length: 101 a.a.        Molecular weight: 10911.69 Da        Isoelectric Point: 5.7134

>AT283004 WP_033733169.1 NZ_CP126681:1597877-1598179 [Pantoea agglomerans]
MGRTLEQLIADEKPEVVADAQAMATEILLNIHLAELREKVQKTQVEMAQALGITQPTVAGMEKPGRDLKLSTLKRYVDAA
GGKLRLVVELPDGSHYGFVV

Download         Length: 303 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References