Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 1481293..1481548 Replicon chromosome
Accession NZ_CP126631
Organism Staphylococcus aureus strain 33-40

Toxin (Protein)


Gene name SprG2 Uniprot ID -
Locus tag QPR37_RS07340 Protein ID WP_063651022.1
Coordinates 1481293..1481400 (+) Length 36 a.a.

Antitoxin (RNA)


Gene name SprF1
Locus tag -
Coordinates 1481411..1481548 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QPR37_RS07320 (QPR37_07320) 1476443..1480228 + 3786 WP_285146592.1 phage tail spike protein -
QPR37_RS07325 (QPR37_07325) 1480218..1480370 + 153 WP_063651023.1 hypothetical protein -
QPR37_RS07330 (QPR37_07330) 1480417..1480704 + 288 WP_001040260.1 hypothetical protein -
QPR37_RS07335 (QPR37_07335) 1480762..1481058 + 297 WP_000539688.1 DUF2951 domain-containing protein -
QPR37_RS07340 (QPR37_07340) 1481293..1481400 + 108 WP_063651022.1 putative holin-like toxin Toxin
- 1481411..1481548 - 138 - - Antitoxin
QPR37_RS07350 (QPR37_07350) 1481598..1481852 + 255 WP_141060376.1 phage holin -
QPR37_RS07355 (QPR37_07355) 1481864..1482619 + 756 WP_259378798.1 CHAP domain-containing protein -
QPR37_RS07360 (QPR37_07360) 1482967..1483893 + 927 WP_000476436.1 bi-component leukocidin LukMF' subunit M -
QPR37_RS07365 (QPR37_07365) 1483895..1484863 + 969 WP_259378800.1 bi-component leukocidin LukMF' subunit F' -
QPR37_RS07370 (QPR37_07370) 1485404..1485835 + 432 WP_285146596.1 Abi family protein -
QPR37_RS07375 (QPR37_07375) 1485922..1486341 + 420 WP_285146992.1 Abi family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - lukS-PV / lukD 1443147..1487723 44576


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Small toxic protein BsrE-like

(3-35)


Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 3828.80 Da        Isoelectric Point: 10.4997

>T282998 WP_063651022.1 NZ_CP126631:1481293-1481400 [Staphylococcus aureus]
VVSVVDALNLMFSFGMFIVVLLGLVIAIVKLNHKK

Download         Length: 108 bp

Antitoxin


Download         Length: 138 bp

>AT282998 NZ_CP126631:c1481548-1481411 [Staphylococcus aureus]
ATTTGATATTTATATTATGGTGTGTTAATTTATATATAGAAAAAGGCAACATGCGCAAACATGTTACCCTAATGAGCCCG
TTAAAAAGACGGTGGCTCAGTTTTGAAATTATTATAAAATAACCATTAACCGTCCAAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References