Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 1226366..1226629 Replicon chromosome
Accession NZ_CP126631
Organism Staphylococcus aureus strain 33-40

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag QPR37_RS05880 Protein ID WP_001802298.1
Coordinates 1226366..1226470 (+) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF2
Locus tag -
Coordinates 1226465..1226629 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QPR37_RS05860 (QPR37_05860) 1221781..1222564 + 784 Protein_1139 ABC transporter ATP-binding protein -
QPR37_RS05865 (QPR37_05865) 1222632..1223489 + 858 WP_063652378.1 HAD family hydrolase -
QPR37_RS05870 (QPR37_05870) 1224544..1225681 + 1138 Protein_1141 SAP domain-containing protein -
QPR37_RS05875 (QPR37_05875) 1225724..1226244 + 521 Protein_1142 recombinase family protein -
QPR37_RS05880 (QPR37_05880) 1226366..1226470 + 105 WP_001802298.1 hypothetical protein Toxin
- 1226465..1226629 - 165 - - Antitoxin
QPR37_RS05890 (QPR37_05890) 1226972..1228063 - 1092 WP_109162112.1 transcriptional regulator -
QPR37_RS05895 (QPR37_05895) 1228329..1229309 - 981 WP_000019739.1 CDF family zinc efflux transporter CzrB -
QPR37_RS05900 (QPR37_05900) 1229311..1229631 - 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
QPR37_RS05905 (QPR37_05905) 1229783..1230448 + 666 WP_001024099.1 SDR family oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T282991 WP_001802298.1 NZ_CP126631:1226366-1226470 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

Antitoxin


Download         Length: 165 bp

>AT282991 NZ_CP126631:c1226629-1226465 [Staphylococcus aureus]
GTAGTAAGTAGAAGCAAAAGATGAAAATCTTCAACTCTTGAAACACAAAAAGGGCAACACTCGGAAACATGTTACCCTAA
TGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAAATGCCGGTCAAAGCGAATAGAAGGT
TATTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References