Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 945740..945924 Replicon chromosome
Accession NZ_CP126631
Organism Staphylococcus aureus strain 33-40

Toxin (Protein)


Gene name SprA2 Uniprot ID -
Locus tag QPR37_RS04425 Protein ID WP_063650394.1
Coordinates 945740..945847 (+) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 945864..945924 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QPR37_RS04400 (QPR37_04400) 941102..941575 + 474 WP_285146305.1 GyrI-like domain-containing protein -
QPR37_RS04405 (QPR37_04405) 941698..942909 - 1212 WP_063650391.1 multidrug effflux MFS transporter -
QPR37_RS04410 (QPR37_04410) 943091..943750 - 660 WP_031927729.1 membrane protein -
QPR37_RS04415 (QPR37_04415) 943810..944952 - 1143 WP_063650393.1 glycerate kinase -
QPR37_RS04420 (QPR37_04420) 945220..945606 + 387 WP_000779353.1 flippase GtxA -
QPR37_RS04425 (QPR37_04425) 945740..945847 + 108 WP_063650394.1 type I toxin-antitoxin system Fst family toxin Toxin
- 945864..945924 - 61 - - Antitoxin
QPR37_RS04430 (QPR37_04430) 946551..948314 + 1764 WP_109162095.1 ABC transporter ATP-binding protein -
QPR37_RS04435 (QPR37_04435) 948339..950073 + 1735 Protein_863 ABC transporter ATP-binding protein -
QPR37_RS04440 (QPR37_04440) 950304..950471 + 168 WP_001798790.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 3982.74 Da        Isoelectric Point: 11.0391

>T282990 WP_063650394.1 NZ_CP126631:945740-945847 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHRLRTRNNKKGDK

Download         Length: 108 bp

Antitoxin


Download         Length: 61 bp

>AT282990 NZ_CP126631:c945924-945864 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References