Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2507253..2507532 Replicon chromosome
Accession NZ_CP126629
Organism Staphylococcus aureus strain 35-42

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag QPL68_RS12135 Protein ID WP_001802298.1
Coordinates 2507253..2507357 (+) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF3
Locus tag -
Coordinates 2507353..2507532 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QPL68_RS12115 (QPL68_12115) 2502668..2503451 + 784 Protein_2347 ABC transporter ATP-binding protein -
QPL68_RS12120 (QPL68_12120) 2503519..2504376 + 858 WP_063652378.1 HAD family hydrolase -
QPL68_RS12125 (QPL68_12125) 2505431..2506568 + 1138 Protein_2349 SAP domain-containing protein -
QPL68_RS12130 (QPL68_12130) 2506611..2507131 + 521 Protein_2350 recombinase family protein -
QPL68_RS12135 (QPL68_12135) 2507253..2507357 + 105 WP_001802298.1 hypothetical protein Toxin
- 2507353..2507532 - 180 - - Antitoxin
QPL68_RS12145 (QPL68_12145) 2507859..2508950 - 1092 WP_109162112.1 transcriptional regulator -
QPL68_RS12150 (QPL68_12150) 2509216..2510196 - 981 WP_000019739.1 CDF family zinc efflux transporter CzrB -
QPL68_RS12155 (QPL68_12155) 2510198..2510518 - 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
QPL68_RS12160 (QPL68_12160) 2510670..2511335 + 666 WP_001024099.1 SDR family oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T282984 WP_001802298.1 NZ_CP126629:2507253-2507357 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

Antitoxin


Download         Length: 180 bp

>AT282984 NZ_CP126629:c2507532-2507353 [Staphylococcus aureus]
GTGTTAAAATATATTTGTAGTAAGTAGAAGCAAAAGATGAAAATCTTCAACTCTTGAAACACAAAAAGGGCAACACTCGG
AAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAAATGCCGGTC
AAAGCGAATAGAAGGTTATT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References