Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2226660..2226844 Replicon chromosome
Accession NZ_CP126629
Organism Staphylococcus aureus strain 35-42

Toxin (Protein)


Gene name SprA2 Uniprot ID -
Locus tag QPL68_RS10680 Protein ID WP_063650394.1
Coordinates 2226660..2226767 (+) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2226784..2226844 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QPL68_RS10655 (QPL68_10655) 2222022..2222495 + 474 WP_285146305.1 GyrI-like domain-containing protein -
QPL68_RS10660 (QPL68_10660) 2222618..2223829 - 1212 WP_063650391.1 multidrug effflux MFS transporter -
QPL68_RS10665 (QPL68_10665) 2224011..2224670 - 660 WP_031927729.1 membrane protein -
QPL68_RS10670 (QPL68_10670) 2224730..2225872 - 1143 WP_063650393.1 glycerate kinase -
QPL68_RS10675 (QPL68_10675) 2226140..2226526 + 387 WP_000779353.1 flippase GtxA -
QPL68_RS10680 (QPL68_10680) 2226660..2226767 + 108 WP_063650394.1 type I toxin-antitoxin system Fst family toxin Toxin
- 2226784..2226844 - 61 - - Antitoxin
QPL68_RS10685 (QPL68_10685) 2227471..2229234 + 1764 WP_109162095.1 ABC transporter ATP-binding protein -
QPL68_RS10690 (QPL68_10690) 2229259..2230993 + 1735 Protein_2071 ABC transporter ATP-binding protein -
QPL68_RS10695 (QPL68_10695) 2231224..2231391 + 168 WP_001798790.1 hypothetical protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin


No domain identified.



Sequences


Toxin        


Download         Length: 36 a.a.        Molecular weight: 3982.74 Da        Isoelectric Point: 11.0391

>T282982 WP_063650394.1 NZ_CP126629:2226660-2226767 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHRLRTRNNKKGDK

Download         Length: 108 bp


Antitoxin


Download         Length: 61 bp

>AT282982 NZ_CP126629:c2226844-2226784 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Download structure file

References