Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 107913..108093 Replicon chromosome
Accession NZ_CP126629
Organism Staphylococcus aureus strain 35-42

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag QPL68_RS00695 Protein ID WP_001801861.1
Coordinates 107998..108093 (-) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 107913..107970 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QPL68_RS00675 (QPL68_00675) 106261..106638 + 378 WP_063651591.1 DUF1433 domain-containing protein -
QPL68_RS00680 (QPL68_00680) 106764..107267 - 504 Protein_98 polysaccharide lyase beta-sandwich domain-containing protein -
QPL68_RS00685 (QPL68_00685) 107626..107781 - 156 WP_174834634.1 hypothetical protein -
QPL68_RS00690 (QPL68_00690) 107777..107875 - 99 Protein_100 hypothetical protein -
- 107913..107970 + 58 - - Antitoxin
QPL68_RS00695 (QPL68_00695) 107998..108093 - 96 WP_001801861.1 type I toxin-antitoxin system Fst family toxin PepA1 Toxin
QPL68_RS00700 (QPL68_00700) 108252..108879 + 628 Protein_102 ImmA/IrrE family metallo-endopeptidase -
QPL68_RS00705 (QPL68_00705) 109077..109649 - 573 WP_063651584.1 hypothetical protein -
QPL68_RS00710 (QPL68_00710) 109750..110091 - 342 WP_141060399.1 DUF3969 family protein -
QPL68_RS00715 (QPL68_00715) 110132..110758 - 627 WP_063651579.1 hypothetical protein -
QPL68_RS00720 (QPL68_00720) 110834..111829 - 996 WP_141060398.1 DUF4352 domain-containing protein -
QPL68_RS00725 (QPL68_00725) 111911..112561 - 651 WP_078316641.1 excalibur calcium-binding domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - hlgA / lukD / hysA 80203..113319 33116


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3554.32 Da        Isoelectric Point: 10.4449

>T282980 WP_001801861.1 NZ_CP126629:c108093-107998 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Download         Length: 96 bp

>T282980 NZ_CP126629:c108093-107998 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin


Download         Length: 58 bp

>AT282980 NZ_CP126629:107913-107970 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References