Detailed information of TA system TA282978

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprG-sprF/-
• Location: 19417..19633
• Replicon: chromosome
• Accession: NZ_CP126629
• Organism: Staphylococcus aureus strain 35-42

Toxin (Protein)

• Gene name: SprG2
• Uniprot ID: -
• Locus tag: QPL68_RS00105
• Protein ID: WP_063651022.1
• Coordinates: 19417..19524 (+)
• Length: 36 a.a.

Antitoxin (RNA)

Gene name	SprF3
Locus tag	-
Coordinates	19579..19633 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
QPL68_RS00085 (QPL68_00085)	14567..18352	+	3786	WP_285146592.1	phage tail spike protein	-
QPL68_RS00090 (QPL68_00090)	18342..18494	+	153	WP_063651023.1	hypothetical protein	-
QPL68_RS00095 (QPL68_00095)	18541..18828	+	288	WP_001040260.1	hypothetical protein	-
QPL68_RS00100 (QPL68_00100)	18886..19182	+	297	WP_000539688.1	DUF2951 domain-containing protein	-
QPL68_RS00105 (QPL68_00105)	19417..19524	+	108	WP_063651022.1	putative holin-like toxin	Toxin
QPL68_RS00110 (QPL68_00110)	19567..19670	-	104	Protein_21	hypothetical protein	-
-	19579..19633	-	55	-	-	Antitoxin
QPL68_RS00115 (QPL68_00115)	19722..19976	+	255	WP_141060376.1	phage holin	-
QPL68_RS00120 (QPL68_00120)	19988..20743	+	756	WP_259378798.1	CHAP domain-containing protein	-
QPL68_RS00125 (QPL68_00125)	21091..22017	+	927	WP_000476436.1	bi-component leukocidin LukMF' subunit M	-
QPL68_RS00130 (QPL68_00130)	22019..22987	+	969	WP_259378800.1	bi-component leukocidin LukMF' subunit F'	-
QPL68_RS00135 (QPL68_00135)	23528..23959	+	432	WP_285146596.1	Abi family protein	-
QPL68_RS00140 (QPL68_00140)	24046..24465	+	420	WP_285146992.1	Abi family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	lukS-PV / lukD	1..25847	25846

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (3-35)

Sequences

Toxin

Protein

• Length: 36 a.a.
• Molecular weight: 3828.80 Da
• Isoelectric Point: 10.4997

>T282978 WP_063651022.1 NZ_CP126629:19417-19524 [Staphylococcus aureus]
VVSVVDALNLMFSFGMFIVVLLGLVIAIVKLNHKK

Nucleotide

• Length: 108 bp

Antitoxin

Nucleotide

• Length: 55 bp

>AT282978 NZ_CP126629:c19633-19579 [Staphylococcus aureus]
AAAAAGGCAACATGCGCAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Structures

Antitoxin