Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2456830..2457014 Replicon chromosome
Accession NZ_CP126627
Organism Staphylococcus aureus strain 17-21

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag QPR40_RS12240 Protein ID WP_000482647.1
Coordinates 2456907..2457014 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2456830..2456890 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QPR40_RS12225 (QPR40_12225) 2452284..2452451 - 168 WP_001790576.1 hypothetical protein -
QPR40_RS12230 (QPR40_12230) 2452682..2454415 - 1734 WP_000486494.1 ABC transporter ATP-binding protein -
QPR40_RS12235 (QPR40_12235) 2454440..2456203 - 1764 WP_001064814.1 ABC transporter ATP-binding protein -
- 2456830..2456890 + 61 - - Antitoxin
QPR40_RS12240 (QPR40_12240) 2456907..2457014 - 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
QPR40_RS12245 (QPR40_12245) 2457148..2457534 - 387 WP_000779360.1 flippase GtxA -
QPR40_RS12250 (QPR40_12250) 2457792..2458934 + 1143 WP_285144360.1 glycerate kinase -
QPR40_RS12255 (QPR40_12255) 2458994..2459653 + 660 WP_285144362.1 hypothetical protein -
QPR40_RS12260 (QPR40_12260) 2459835..2461046 + 1212 WP_001192075.1 multidrug effflux MFS transporter -
QPR40_RS12265 (QPR40_12265) 2461169..2461642 - 474 WP_000456489.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T282975 WP_000482647.1 NZ_CP126627:c2457014-2456907 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

Antitoxin


Download         Length: 61 bp

>AT282975 NZ_CP126627:2456830-2456890 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References