Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/HigB-HigA
Location 4746302..4746891 Replicon chromosome
Accession NZ_CP126568
Organism Xanthomonas oryzae pv. oryzicola strain HB8

Toxin (Protein)


Gene name graT Uniprot ID A0A0C5V8F2
Locus tag QPJ94_RS21680 Protein ID WP_024712137.1
Coordinates 4746302..4746583 (+) Length 94 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag QPJ94_RS21685 Protein ID WP_011260746.1
Coordinates 4746601..4746891 (+) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QPJ94_RS21675 4743946..4746207 + 2262 WP_024712136.1 exodeoxyribonuclease V subunit alpha -
QPJ94_RS21680 4746302..4746583 + 282 WP_024712137.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
QPJ94_RS21685 4746601..4746891 + 291 WP_011260746.1 HigA family addiction module antitoxin Antitoxin
QPJ94_RS21690 4747829..4749223 + 1395 WP_149621925.1 type III secretion system effector XopQ -
QPJ94_RS21695 4749326..4749513 - 188 Protein_4116 hypothetical protein -
QPJ94_RS21700 4749674..4750006 - 333 WP_011260743.1 hypothetical protein -
QPJ94_RS21705 4750261..4750566 + 306 WP_224229802.1 hypothetical protein -
QPJ94_RS21710 4750716..4751138 + 423 WP_044751863.1 PAAR domain-containing protein -
QPJ94_RS21715 4751141..4751617 + 477 WP_024712141.1 DUF4123 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-1

(4-93)

Antitoxin

Cro/C1-type helix-turn-helix domain

(14-68)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 11125.91 Da        Isoelectric Point: 10.5318

>T282967 WP_024712137.1 NZ_CP126568:4746302-4746583 [Xanthomonas oryzae pv. oryzicola]
MIRSFIDKDAEKIWLGERSRRLPADIQLVARRKLRMLNAAAHLDDLRIPPANRLEALKGQRRGQYNIRINDQWRICFRWM
EGDVVQVEIVDYH

Download         Length: 282 bp

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10420.07 Da        Isoelectric Point: 7.2040

>AT282967 WP_011260746.1 NZ_CP126568:4746601-4746891 [Xanthomonas oryzae pv. oryzicola]
MTVLPNIHPGDILLEEFLEPLGISQNALARATGVPPRRINEIVLGKRGITADTAVRLAAALGTSERFWLGLQADYELEQA
HRALGDLPARIKRLAA

Download         Length: 291 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0C5V8F2

Antitoxin

Source ID Structure

References