Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-YefM
Location 4144937..4145439 Replicon chromosome
Accession NZ_CP126335
Organism Proteus vulgaris strain TAF3

Toxin (Protein)


Gene name yoeB Uniprot ID A0A6G6SM64
Locus tag QN092_RS19610 Protein ID WP_072068852.1
Coordinates 4145185..4145439 (+) Length 85 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag QN092_RS19605 Protein ID WP_072068851.1
Coordinates 4144937..4145188 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QN092_RS19575 (QN092_19575) 4140353..4141087 + 735 WP_072068845.1 phosphate signaling complex protein PhoU -
QN092_RS19580 (QN092_19580) 4141303..4142142 + 840 WP_197269777.1 ABC transporter substrate-binding protein -
QN092_RS19585 (QN092_19585) 4142250..4142987 + 738 WP_284551259.1 amino acid ABC transporter permease -
QN092_RS19590 (QN092_19590) 4142989..4143735 + 747 WP_115351109.1 amino acid ABC transporter permease -
QN092_RS19595 (QN092_19595) 4143728..4143935 - 208 Protein_3811 IS3 family transposase -
QN092_RS19600 (QN092_19600) 4143986..4144390 - 405 WP_072068849.1 DUF1240 domain-containing protein -
QN092_RS19605 (QN092_19605) 4144937..4145188 + 252 WP_072068851.1 YoeB-YefM toxin-antitoxin system antitoxin YefM Antitoxin
QN092_RS19610 (QN092_19610) 4145185..4145439 + 255 WP_072068852.1 Txe/YoeB family addiction module toxin Toxin
QN092_RS19615 (QN092_19615) 4145596..4146954 + 1359 WP_072068853.1 NCS2 family permease -
QN092_RS19620 (QN092_19620) 4147034..4147345 + 312 WP_072068854.1 monooxygenase -
QN092_RS19625 (QN092_19625) 4147395..4147943 - 549 WP_284551260.1 GNAT family N-acetyltransferase -
QN092_RS19630 (QN092_19630) 4147946..4149418 - 1473 WP_072068856.1 glycosyltransferase family 39 protein -
QN092_RS19635 (QN092_19635) 4149607..4150104 + 498 WP_072068857.1 Der GTPase-activating protein YihI -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 10226.86 Da        Isoelectric Point: 9.9664

>T282811 WP_072068852.1 NZ_CP126335:4145185-4145439 [Proteus vulgaris]
MKLIFSEQSWSDYLYWQQMDKRIIKRINELIKDIKRTPFSGIGKPEPLKHNLAGFWSRRITDEHRLIYRITDPAIEIASC
RYHY

Download         Length: 255 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9463.77 Da        Isoelectric Point: 4.4354

>AT282811 WP_072068851.1 NZ_CP126335:4144937-4145188 [Proteus vulgaris]
MKTINYTEARQNLTSIMNETIDDRVPIMITRQKGIPCVLLSLDEYQALEETAYLLRSPANARHLLDSIDELNQGKGIEKD
ITE

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A6G6SM64

Antitoxin

Source ID Structure

References