Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-YefM
Location 85568..86076 Replicon chromosome
Accession NZ_CP126279
Organism Curtobacterium sp. MCBD17_035

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag DEI93_RS00420 Protein ID WP_111119569.1
Coordinates 85568..85828 (-) Length 87 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag DEI93_RS00425 Protein ID WP_111010329.1
Coordinates 85825..86076 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DEI93_RS00395 (DEI93_00395) 81025..81849 + 825 WP_111011977.1 carbohydrate ABC transporter permease -
DEI93_RS00400 (DEI93_00400) 81884..82687 - 804 WP_220037868.1 ATP-binding cassette domain-containing protein -
DEI93_RS00405 (DEI93_00405) 82693..83415 - 723 WP_220037867.1 GntR family transcriptional regulator -
DEI93_RS00410 (DEI93_00410) 83526..84515 - 990 WP_111119570.1 acryloyl-CoA reductase -
DEI93_RS00415 (DEI93_00415) 84546..85529 - 984 WP_111010331.1 aldo/keto reductase -
DEI93_RS00420 (DEI93_00420) 85568..85828 - 261 WP_111119569.1 Txe/YoeB family addiction module toxin Toxin
DEI93_RS00425 (DEI93_00425) 85825..86076 - 252 WP_111010329.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
DEI93_RS00430 (DEI93_00430) 86134..87162 - 1029 WP_111011990.1 6-phosphofructokinase -
DEI93_RS00435 (DEI93_00435) 87317..88258 + 942 WP_258372218.1 DNA-3-methyladenine glycosylase 2 family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-83)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 10410.61 Da        Isoelectric Point: 8.0642

>T282736 WP_111119569.1 NZ_CP126279:c85828-85568 [Curtobacterium sp. MCBD17_035]
VRYVWDDAAWADYEWWQQQDRKIVKRINGLLRDIARNGNEGIGKPEPLKHGFRGYWSRRITDEHRLAYRVTDDSVLIAQC
RYHHDE

Download         Length: 261 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9479.48 Da        Isoelectric Point: 4.4652

>AT282736 WP_111010329.1 NZ_CP126279:c86076-85825 [Curtobacterium sp. MCBD17_035]
MRILSYSETRSHFAETLNAVTDDREEVVVTRAGHESVVLVSLDDYESLKETAYLLRNPANARRLLASIERLERGEGTERD
LDE

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References