Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-YefM
Location 94373..94881 Replicon chromosome
Accession NZ_CP126275
Organism Curtobacterium sp. MCBD17_003

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag DEI88_RS00475 Protein ID WP_111035709.1
Coordinates 94373..94633 (-) Length 87 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag DEI88_RS00480 Protein ID WP_111010329.1
Coordinates 94630..94881 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DEI88_RS00450 (DEI88_000450) 89515..90618 - 1104 WP_111035714.1 M20 family metallopeptidase -
DEI88_RS00455 (DEI88_000455) 90688..91491 - 804 WP_220037224.1 ATP-binding cassette domain-containing protein -
DEI88_RS00460 (DEI88_000460) 91497..92219 - 723 WP_111035712.1 GntR family transcriptional regulator -
DEI88_RS00465 (DEI88_000465) 92331..93320 - 990 WP_111035711.1 acryloyl-CoA reductase -
DEI88_RS00470 (DEI88_000470) 93351..94334 - 984 WP_111035710.1 aldo/keto reductase -
DEI88_RS00475 (DEI88_000475) 94373..94633 - 261 WP_111035709.1 Txe/YoeB family addiction module toxin Toxin
DEI88_RS00480 (DEI88_000480) 94630..94881 - 252 WP_111010329.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
DEI88_RS00485 (DEI88_000485) 94939..95967 - 1029 WP_111010328.1 6-phosphofructokinase -
DEI88_RS00490 (DEI88_000490) 96121..97062 + 942 WP_258368583.1 DNA-3-methyladenine glycosylase 2 family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-83)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 10328.55 Da        Isoelectric Point: 8.0720

>T282735 WP_111035709.1 NZ_CP126275:c94633-94373 [Curtobacterium sp. MCBD17_003]
VKYVWDDAAWADSEWWQQQDRKIVKRINGLLRDIARNGNEGIGRPEPLKHGLRGYWSRRITDEHRLVYRVTDDSVLIAQC
RYHHDE

Download         Length: 261 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9479.48 Da        Isoelectric Point: 4.4652

>AT282735 WP_111010329.1 NZ_CP126275:c94881-94630 [Curtobacterium sp. MCBD17_003]
MRILSYSETRSHFAETLNAVTDDREEVVVTRAGHESVVLVSLDDYESLKETAYLLRNPANARRLLASIERLERGEGTERD
LDE

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References