Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/COG4683-HTH_37
Location 3052975..3053636 Replicon chromosome
Accession NZ_CP126169
Organism Rahnella bonaserana strain L46

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag QNM34_RS13810 Protein ID WP_284002192.1
Coordinates 3053277..3053636 (-) Length 120 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag QNM34_RS13805 Protein ID WP_217172903.1
Coordinates 3052975..3053277 (-) Length 101 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QNM34_RS13795 (QNM34_13795) 3050687..3051975 - 1289 Protein_2705 TrbI/VirB10 family protein -
QNM34_RS13800 (QNM34_13800) 3051978..3052384 - 407 Protein_2706 TrbG/VirB9 family P-type conjugative transfer protein -
QNM34_RS13805 (QNM34_13805) 3052975..3053277 - 303 WP_217172903.1 XRE family transcriptional regulator Antitoxin
QNM34_RS13810 (QNM34_13810) 3053277..3053636 - 360 WP_284002192.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
QNM34_RS13815 (QNM34_13815) 3053847..3053999 - 153 WP_217172905.1 Hok/Gef family protein -
QNM34_RS13820 (QNM34_13820) 3054346..3055659 + 1314 WP_284002195.1 FAD-binding oxidoreductase -
QNM34_RS13825 (QNM34_13825) 3055702..3056358 - 657 WP_120161833.1 methionine ABC transporter permease -
QNM34_RS13830 (QNM34_13830) 3056339..3057493 - 1155 WP_217172907.1 methionine ABC transporter ATP-binding protein -
QNM34_RS13835 (QNM34_13835) 3057504..3058346 - 843 WP_284002197.1 MetQ/NlpA family lipoprotein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(12-106)

Antitoxin

HigA2-like, helix-turn-helix domain

(17-88)


Sequences

Toxin        


Download         Length: 120 a.a.        Molecular weight: 13638.66 Da        Isoelectric Point: 7.9097

>T282726 WP_284002192.1 NZ_CP126169:c3053636-3053277 [Rahnella bonaserana]
VWIINTTERFDDWFDSLDHVDQASVLALAIVLKDKGPALSRPYADTVNNSCHRNMKELRILSKGEPIRAFFAFDPLRRGI
LLCAGHKAGNEKRFYNVMIPVADNEFSRHLNTIKEKELP

Download         Length: 360 bp

Antitoxin


Download         Length: 101 a.a.        Molecular weight: 10926.74 Da        Isoelectric Point: 5.1879

>AT282726 WP_217172903.1 NZ_CP126169:c3053277-3052975 [Rahnella bonaserana]
MSRTLEELLASVKPEVAAQAQAMAADILITIELAELRERMNKTQCELAETLGIKQPTVAGMEKPGRDLKLSTLKRYVEAA
GGKLRLEIDLPDGSHFGFAM

Download         Length: 303 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References