Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/HigB-HigA
Location 1474035..1474756 Replicon chromosome
Accession NZ_CP126169
Organism Rahnella bonaserana strain L46

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag QNM34_RS06665 Protein ID WP_284005595.1
Coordinates 1474445..1474756 (-) Length 104 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag QNM34_RS06660 Protein ID WP_217174940.1
Coordinates 1474035..1474448 (-) Length 138 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QNM34_RS06650 (QNM34_06650) 1470086..1472263 + 2178 WP_217174938.1 type I secretion system permease/ATPase -
QNM34_RS06655 (QNM34_06655) 1472281..1473450 + 1170 WP_217174939.1 HlyD family efflux transporter periplasmic adaptor subunit -
QNM34_RS06660 (QNM34_06660) 1474035..1474448 - 414 WP_217174940.1 helix-turn-helix domain-containing protein Antitoxin
QNM34_RS06665 (QNM34_06665) 1474445..1474756 - 312 WP_284005595.1 type II toxin-antitoxin system HigB family toxin Toxin
QNM34_RS06670 (QNM34_06670) 1474854..1476884 - 2031 WP_284005596.1 DUF4034 domain-containing protein -
QNM34_RS06675 (QNM34_06675) 1477661..1478788 + 1128 WP_217174943.1 porin OmpC -
QNM34_RS06680 (QNM34_06680) 1478959..1479426 + 468 WP_217174944.1 nuclear transport factor 2 family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, mRNA interferase HigB

(20-93)

Antitoxin

Antitoxin HigA

(2-137)


Sequences

Toxin        


Download         Length: 104 a.a.        Molecular weight: 12238.08 Da        Isoelectric Point: 10.2414

>T282722 WP_284005595.1 NZ_CP126169:c1474756-1474445 [Rahnella bonaserana]
MHVIAKEAFDRAMRQYPNDKTALLATYRGLKEGDYPTPDSLKSVFSSLDNFRYRPKWWVINVGGNNLRLIAYINFVNKRV
YVKHIVTHALYDQLNKHYRIYTQ

Download         Length: 312 bp

Antitoxin


Download         Length: 138 a.a.        Molecular weight: 15203.36 Da        Isoelectric Point: 4.9713

>AT282722 WP_217174940.1 NZ_CP126169:c1474448-1474035 [Rahnella bonaserana]
MIAEAIEASKALVKAVPLLGGSTSTADYKSALELIDYLIEHDDENPLIEFLSAKIESYERQHTDFVTFNQAVGNLPRGVE
ALRQLMKDYGLKQNDLREEIGGKSLVSQILSGKRSLTVEHIRALAVRFNVPTSLFID

Download         Length: 414 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References