28256

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprG3-SprA2AS/-
Location 2178267..2178465 Replicon chromosome
Accession NC_018608
Organism Staphylococcus aureus 08BA02176

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag C248_RS10850 Protein ID WP_001802298.1
Coordinates 2178361..2178465 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2178267..2178305 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C248_RS10830 2174387..2175052 - 666 WP_001024099.1 SDR family oxidoreductase -
C248_RS10835 2175204..2175524 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
C248_RS10840 2175526..2176506 + 981 WP_000019735.1 CDF family zinc efflux transporter CzrB -
C248_RS10845 2176772..2177863 + 1092 WP_000495673.1 hypothetical protein -
- 2178267..2178305 + 39 - - Antitoxin
C248_RS10850 2178361..2178465 - 105 WP_001802298.1 hypothetical protein Toxin
C248_RS14500 2179145..2179303 + 159 WP_001792784.1 hypothetical protein -
C248_RS10855 2179739..2179831 + 93 WP_000220902.1 hypothetical protein -
C248_RS10860 2179961..2180818 - 858 WP_000370942.1 Cof-type HAD-IIB family hydrolase -
C248_RS10865 2180886..2181668 - 783 WP_000908191.1 ABC transporter ATP-binding protein -
C248_RS10870 2181958..2182566 - 609 WP_000101714.1 TIR domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T28256 WP_001802298.1 NC_018608:c2178465-2178361 [Staphylococcus aureus 08BA02176]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T28256 NC_018608:c2178465-2178361 [Staphylococcus aureus 08BA02176]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 39 bp

>AT28256 NC_018608:2178267-2178305 [Staphylococcus aureus 08BA02176]
AACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTGAC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References